Evidence map›Paper›PMID 33665188›Full record

ArticleFrontiers in cell and developmental biology2021

Genome-Wide Analysis of Differentially Expressed miRNAs and Their Associated Regulatory Networks in Lenses Deficient for the Congenital Cataract-Linked Tudor Domain Containing Protein TDRD7.

Deepti Anand, Salma Al Saai, Sanjaya K Shrestha, Carrie E Barnum, Shinichiro Chuma, Salil A Lachke

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Identification of co-segregatingFrontiers in medicine · 2025
    Article
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  12. Article
  13. Specific microRNA Signature Kinetics inInternational journal of molecular sciences · 2023
    Article
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  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Deepti AnandDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Salma Al SaaiDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Sanjaya K ShresthaDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Carrie E BarnumDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Shinichiro ChumaInstitute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan.
Salil A LachkeDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
University of Delaware · USKyoto University · JP

Funding

POST TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN THE LENS (LENS GENE EXPRESSIONR01EY021505 · NEI · WASHINGTON UNIVERSITY · PI LACHKE, SALIL · 2011 to 2024
$5.3M
RNA-binding proteins in early eye development.R01EY029770 · NEI · UNIVERSITY OF DELAWARE · PI LACHKE, SALIL · 2019 to 2023
$1.7M
NEI NIH HHS R01 EY021505NEI NIH HHS R01 EY029770
6 · The paper itself

Abstract

Mutations/deficiency of

Indexed as

cataracteye development and functiongene regulatory networkslens aberrationmicroarraymicroRNATDRD7

Identifiers

PMID33665188
PMCPMC7921330
OpenAlexW3130458264

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.