Evidence map›Paper›PMID 33668117›Full record

ReviewInternational journal of molecular sciences2021

Trogocytosis between Non-Immune Cells for Cell Clearance, and among Immune-Related Cells for Modulating Immune Responses and Autoimmunity.

Ko-Jen Li, Cheng-Han Wu, Cheng-Hsun Lu, Chieh-Yu Shen, Yu-Min Kuo, Chang-Youh Tsai, Song-Chou Hsieh, Chia-Li Yu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Induced proximity at the cell surface.Nature biotechnology · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Pathogens (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Review
  9. Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ko-Jen LiDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10002, Taiwan.ORCID 0000-0002-4544-4620
Cheng-Han WuDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Cheng-Hsun LuDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Chieh-Yu ShenDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10002, Taiwan.ORCID 0000-0002-3218-0689
Yu-Min KuoDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Chang-Youh TsaiDivision of Allergy, Immunology & Rheumatology, Taipei Veterans General Hospital, Taipei 11210, Taiwan.ORCID 0000-0002-4154-4018
Song-Chou HsiehDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Chia-Li YuDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10002, Taiwan.ORCID 0000-0003-4988-0400

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term trogocytosis refers to a rapid bidirectional and active transfer of surface membrane fragment and associated proteins between cells. The trogocytosis requires cell-cell contact, and exhibits fast kinetics and the limited lifetime of the transferred molecules on the surface of the acceptor cells. The biological actions of trogocytosis include information exchange, cell clearance of unwanted tissues in embryonic development, immunoregulation, cancer surveillance/evasion, allogeneic cell survival and infectious pathogen killing or intercellular transmission. In the present review, we will extensively review all these aspects. In addition to its biological significance, aberrant trogocytosis in the immune system leading to autoimmunity and immune-mediated inflammatory diseases will also be discussed. Finally, the prospective investigations for further understanding the molecular basis of trogocytosis and its clinical applications will also be proposed.

Indexed as

AnimalsAntigen PresentationAutoimmunityCell CommunicationCell MembraneHumansImmune SystemLymphocyte ActivationLymphocytesamoebic trogocytosis, cell clearanceantibody-dependent cell-mediated cytotoxicityantigen modificationchimeric antigen receptor T lymphocyteimmune plasticityoncologic trogocytosistrogocytosistumor evasiontumor surveillance

Identifiers

PMID33668117
PMCPMC7956485

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.