Evidence map›Paper›PMID 33668486›Full record

ReviewPathogens (Basel, Switzerland)2021

Regulation of Latency and Reactivation by Human Cytomegalovirus miRNAs.

Nicole L Diggins, Rebecca L Skalsky, Meaghan H Hancock

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Mechanisms and Determinants of CMV Reactivation in Kidney Transplantation.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Viral miRNA regulation of host gene expression.Seminars in cell & developmental biology · 2023
    Review
  13. Review
  14. Hematopoietic stem cells and betaherpesvirus latency.Frontiers in cellular and infection microbiology · 2023
    Review
  15. Review
  16. Article
  17. Human Cytomegalovirus miR-UL70-3p Downregulates the HInternational journal of molecular sciences · 2021
    Article
  18. Review
  19. Immune Prophylaxis and Therapy for Human Cytomegalovirus Infection.International journal of molecular sciences · 2021
    Review
  20. Cytomegalovirus (CMV) Infection and Latency.Pathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicole L DigginsVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.
Rebecca L SkalskyVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.
Meaghan H HancockVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.ORCID 0000-0003-2945-0147

Funding

microRNA Regulation of Gamma-herpesvirus Latency and ReactivationR01AI143620 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI SKALSKY, REBECCA L · 2019 to 2023
$2.5M
NIAID NIH HHS R01 AI143620NIH HHS AI127335NIH HHS AI143620NIH HHS AI21640
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) encodes 22 mature microRNAs (miRNAs), which regulate a myriad of cellular processes, including vesicular trafficking, cell cycle progression, apoptosis, and immune evasion, as well as viral gene expression. Recent evidence points to a critical role for HCMV miRNAs in mediating latency in CD34

Indexed as

cytomegaloviruslatencymiRNAsignaling

Identifiers

PMID33668486
PMCPMC7918750

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.