Evidence map›Paper›PMID 33668947›Full record

ArticleGenes2021

Angiotensinogen Gene Missense Polymorphisms (rs699 and rs4762): The Association of End-Stage Renal Failure Risk with Type 2 Diabetes and Hypertension in Egyptians.

Islam M El-Garawani, Eman M Shaheen, Hesham R El-Seedi, Shaden M A Khalifa, Gaber A M Mersal, Mahmoud M Emara, Zeinab A Kasemy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genetic Variations inJournal of clinical medicine · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Islam M El-GarawaniDepartment of Zoology, Faculty of Science, Menoufia University, Menoufia 32511, Egypt.
Eman M ShaheenDepartment of Zoology, Faculty of Science, Menoufia University, Menoufia 32511, Egypt.
Hesham R El-SeediInternational Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China.
Shaden M A KhalifaDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-10691 Stockholm, Sweden.
Gaber A M MersalChemistry Department, College of Science, Taif University, Taif 21944, Saudi Arabia.
Mahmoud M EmaraDepartment of Clinical Internal Medicine, Faculty of Medicine, Menoufia University, Menoufia 32511, Egypt.
Zeinab A KasemyDepartment of Public Health and Community Medicine, Faculty of Medicine, Menoufia University, Menoufia 32511, Egypt.
Menoufia University · EGJiangsu University · CNStockholm University · SETaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) and hypertension are common chronic diseases mainly associated with the development and progression of end-stage renal disease (ESRD) leading to morbidity and mortality. Gene polymorphisms linked to the renin-angiotensin (

Indexed as

Mutation, MissenseAgedAngiotensinogenDiabetes Mellitus, Type 2EgyptFemaleGene FrequencyGenetic Predisposition to DiseaseHumansHypertensionKidney Failure, ChronicMaleMiddle AgedPolymorphism, Single NucleotideAGT protein, humanAngiotensinogenangiotensinogen polymorphismdiabetic nephropathyend-stage renal failurehypertensionrs4762rs699

Identifiers

PMID33668947
PMCPMC7996594
OpenAlexW3132039936

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.