Evidence map›Paper›PMID 33670533›Full record

ArticleInternational journal of molecular sciences2021

BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice.

Wineke Bakker, Calinda K E Dingenouts, Kirsten Lodder, Karien C Wiesmeijer, Alwin de Jong, Kondababu Kurakula, Hans-Jurgen J Mager, Anke M Smits, Margreet R de Vries, Paul H A Quax and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Arteriogenesis and Therapeutic Angiogenesis-An Update.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Wineke BakkerDepartment of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Calinda K E DingenoutsDepartment of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Kirsten LodderDepartment of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Karien C WiesmeijerDepartment of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Alwin de JongDepartment of Surgery, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Kondababu KurakulaDepartment of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.ORCID 0000-0002-9830-6344
Hans-Jurgen J MagerSt. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Anke M SmitsDepartment of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.ORCID 0000-0002-2443-8547
Margreet R de VriesDepartment of Surgery, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.ORCID 0000-0002-3648-9130
Paul H A QuaxDepartment of Surgery, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.ORCID 0000-0002-6853-5760
Marie José T H GoumansDepartment of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.ORCID 0000-0001-9344-6746
Leiden University Medical Center · NLSt. Antonius Ziekenhuis · NL

Funding

Dutch Cardiovascular Alliance CVON-PHAEDRA-Impact consortiumDutch Heart Foundation NHS2009B063NIRM FES0908
6 · The paper itself

Abstract

Hereditary hemorrhagic telangiectasia type 1 (HHT1) is a severe vascular disorder caused by mutations in the TGFβ/BMP co-receptor

Indexed as

Disease Models, AnimalAnimalsBone Morphogenetic Protein ReceptorsCells, CulturedEndoglinFemaleHeterozygoteHumansMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutMyocardial InfarctionPyrazolesPyrimidinesBone Morphogenetic Protein ReceptorsEndoglinLDN 193189PyrazolesPyrimidinesendoglinhind limb ischemiamyocardial infarctionneovascularizationtissue repairtransforming growth factor-β

Identifiers

PMID33670533
PMCPMC7922601
OpenAlexW3131114502

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.