Evidence map›Paper›PMID 33673244›Full record

ArticleInternational journal of molecular sciences2021

A Toxic Synergy between Aluminium and Amyloid Beta in Yeast.

Jamieson B Mcdonald, Sudip Dhakal, Ian Macreadie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. AlClFrontiers in toxicology · 2025
    Article
  3. Review
  4. Molecular Mechanisms of Alzheimer's Disease III.International journal of molecular sciences · 2022
    Article
  5. The Use of Yeast in Biosensing.Microorganisms · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jamieson B McdonaldSchool of Science, RMIT University, Bundoora, VIC 3083, Australia.
Sudip DhakalSchool of Science, RMIT University, Bundoora, VIC 3083, Australia.ORCID 0000-0002-5885-4653
Ian MacreadieSchool of Science, RMIT University, Bundoora, VIC 3083, Australia.ORCID 0000-0001-5335-7220
RMIT University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD), the most prevalent, age-related, neurodegenerative disease, is associated with the accumulation of amyloid beta (Aβ) and oxidative stress. However, the sporadic nature of late-onset AD has suggested that other factors, such as aluminium may be involved. Aluminium (Al

Indexed as

Oxidative StressAluminumAmyloid beta-PeptidesHumansPeptide FragmentsSaccharomyces cerevisiaeAluminumAmyloid beta-Peptidesamyloid beta-protein (1-42)Peptide FragmentsaluminiumAlzheimer’s diseaseamyloid betaFenton chemistryironoxidative stressyeast

Identifiers

PMID33673244
PMCPMC7918211
OpenAlexW3129349656

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.