Evidence map›Paper›PMID 33673393›Full record

ArticleToxins2021

Shiga Toxin (Stx)-Binding Glycosphingolipids of Primary Human Renal Cortical Epithelial Cells (pHRCEpiCs) and Stx-Mediated Cytotoxicity.

Johanna Detzner, Elisabeth Krojnewski, Gottfried Pohlentz, Daniel Steil, Hans-Ulrich Humpf, Alexander Mellmann, Helge Karch, Johannes Müthing

Open access · goldAbstract readComparative Study
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. EnterohemorrhagicInternational journal of molecular sciences · 2022
    Review
  7. Ingenious Action ofMicroorganisms · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Johanna DetznerInstitute of Hygiene, University of Münster, D-48149 Münster, Germany.
Elisabeth KrojnewskiInstitute of Hygiene, University of Münster, D-48149 Münster, Germany.
Gottfried PohlentzInstitute of Hygiene, University of Münster, D-48149 Münster, Germany.
Daniel SteilInstitute of Hygiene, University of Münster, D-48149 Münster, Germany.
Hans-Ulrich HumpfInstitute of Food Chemistry, University of Münster, D-48149 Münster, Germany.ORCID 0000-0003-3296-3058
Alexander MellmannInstitute of Hygiene, University of Münster, D-48149 Münster, Germany.ORCID 0000-0002-0649-5185
Helge KarchInstitute of Hygiene, University of Münster, D-48149 Münster, Germany.
Johannes MüthingInstitute of Hygiene, University of Münster, D-48149 Münster, Germany.ORCID 0000-0001-9958-3514
University of Münster · DE

Funding

Deutsche Forschungsgemeinschaft MU845/7-1 with reference number 404813761 (J.M.) and SFB 1009 with ID 194468054 (A.M.)
6 · The paper itself

Abstract

Human kidney epithelial cells are supposed to be directly involved in the pathogenesis of the hemolytic-uremic syndrome (HUS) caused by Shiga toxin (Stx)-producing enterohemorrhagic

Indexed as

AnimalsCell SurvivalChlorocebus aethiopsEpithelial CellsEscherichia coli InfectionsGlobosidesHemolytic-Uremic SyndromeHumansKidney CortexMembrane MicrodomainsPrimary Cell CultureProtein BindingShiga-Toxigenic Escherichia coliShiga Toxin 1Shiga Toxin 2TrihexosylceramidesGlobosidesglobotetraosylceramideglobotriaosylceramideShiga Toxin 1Shiga Toxin 2TrihexosylceramidesEHECglycolipidskidney cortical epithelial cellspHRCEpiCsreceptorShiga toxinSTECStx1aStx2a

Identifiers

PMID33673393
PMCPMC7918848
OpenAlexW3129942338

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.