Evidence map›Paper›PMID 33673567›Full record

Trial reportNutrients2021

Placebo Effect of Caffeine on Substrate Oxidation during Exercise.

Jorge Gutiérrez-Hellín, Carlos Ruiz-Moreno, Millán Aguilar-Navarro, Alejandro Muñoz, David Varillas-Delgado, Francisco J Amaro-Gahete, Justin D Roberts, Juan Del Coso

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Jorge Gutiérrez-HellínExercise and Sport Science, Faculty of Health Sciences, Universidad Francisco de Vitoria, 28223 Pozuelo, Spain.ORCID 0000-0001-9721-2269
Carlos Ruiz-MorenoExercise Physiology Laboratory, Camilo José Cela University, 28692 Villanueva de la Cañada, Spain.ORCID 0000-0003-0644-8132
Millán Aguilar-NavarroExercise and Sport Science, Faculty of Health Sciences, Universidad Francisco de Vitoria, 28223 Pozuelo, Spain.ORCID 0000-0001-9130-9182
Alejandro MuñozExercise and Sport Science, Faculty of Health Sciences, Universidad Francisco de Vitoria, 28223 Pozuelo, Spain.ORCID 0000-0001-7679-4116
David Varillas-DelgadoFaculty of Medicine, Universidad Francisco de Vitoria, 28223 Pozuelo, Spain.ORCID 0000-0001-5026-2701
Francisco J Amaro-GaheteDepartment of Medical Physiology, Faculty of Medicine, University of Granada, 18 Granada, Spain.ORCID 0000-0002-7207-9016
Justin D RobertsCambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport Science, Anglia Ruskin University, Cambridge CB1 1PT, UK.ORCID 0000-0002-3169-2041
Juan Del CosoCentre for Sport Studies, Rey Juan Carlos University, 28943 Fuenlabrada, Spain.ORCID 0000-0002-5785-984X
Universidad Francisco de Vitoria · ESAnglia Ruskin University · GBCamilo José Cela University · ESUniversidad de Granada · ESUniversidad Rey Juan Carlos · ES

Funding

Universidad Francisco de Vitoria UFV-18/2020
6 · The paper itself

Abstract

By using deceptive experiments in which participants are informed that they received caffeine when, in fact, they received an inert substance (i.e., placebo), several investigations have demonstrated that exercise performance can be enhanced to a similar degree as a known caffeine dose. This 'placebo effect' phenomenon may be part of the mechanisms explaining caffeine's ergogenicity in exercise. However, there is no study that has established whether the placebo effect of caffeine is also present for other benefits obtained with acute caffeine intake, such as enhanced fat oxidation during exercise. Therefore, the aim of this investigation was to investigate the placebo effect of caffeine on fat oxidation during exercise. Twelve young men participated in a deceptive double-blind cross-over experiment. Each participant completed three identical trials consisting of a step incremental exercise test from 30 to 80% of V.O

Indexed as

Adipose TissueAdultCaffeineCross-Over StudiesDouble-Blind MethodEnergy MetabolismExerciseHumansMaleOxidation-ReductionOxidative StressYoung AdultCaffeinecarbohydratedietary supplementergogenic aidpsychological advantage

Identifiers

PMID33673567
PMCPMC7997444
OpenAlexW3133934101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.