Evidence map›Paper›PMID 33673808›Full record

ArticleBMC nephrology2021

Renal transplantation outcomes in obese patients: a French cohort-based study.

Y Foucher, M Lorent, L Albano, S Roux, V Pernin, M Le Quintrec, C Legendre, F Buron, E Morelon, S Girerd and 8 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. KiT-GENIE, the French genetic biobank of kidney transplantation.European journal of human genetics : EJHG · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Y FoucherINSERM UMR 1246 - SPHERE, Nantes University, Tours University, Nantes, France. Yohann.Foucher@univ-nantes.fr.ORCID 0000-0003-0330-7457
M LorentINSERM UMR 1246 - SPHERE, Nantes University, Tours University, Nantes, France.
L AlbanoDepartment of Nephrology and Renal Transplantation, Hospital Pasteur, Nice, France.
S RouxINSERM UMR 1246 - SPHERE, Nantes University, Tours University, Nantes, France.
V PerninNephrology, Dialysis and Transplantation Department, Lapeyronie University Hospital, Montpellier, France.
M Le QuintrecNephrology, Dialysis and Transplantation Department, Lapeyronie University Hospital, Montpellier, France.
C LegendreKidney Transplant Center, Necker University Hospital, APHP, RTRS « Centaure », Paris Descartes and Sorbonne Paris Cité Universities, Paris, France.
F BuronNephrology, Transplantation and Clinical Immunology Department, RTRS « Centaure », Edouard Herriot University Hospital, Hospices Civils, Lyon, France.
E MorelonNephrology, Transplantation and Clinical Immunology Department, RTRS « Centaure », Edouard Herriot University Hospital, Hospices Civils, Lyon, France.
S GirerdRenal Transplantation Department, Brabois University Hospital, Nancy, France.
M LadrièreRenal Transplantation Department, Brabois University Hospital, Nancy, France.
D GlotzDepartment of Nephrology and Renal Transplantation, CHU Paris-GH St-Louis Lariboisière F. Widal, Paris, France.
C LefaucherDepartment of Nephrology and Renal Transplantation, CHU Paris-GH St-Louis Lariboisière F. Widal, Paris, France.
C KerleauCentre Hospitalier Universitaire de Nantes, Nantes, France.
J DantalCentre Hospitalier Universitaire de Nantes, Nantes, France.
J BranchereauCentre Hospitalier Universitaire de Nantes, Nantes, France.
M GiralCentre Hospitalier Universitaire de Nantes, Nantes, France.
DIVAT consortium
Inserm · FRUniversité de Tours · FRCentre Hospitalier Régional et Universitaire de Nancy · FRHôpital Fernand-Widal · FRHôpital Lapeyronie · FRHospices Civils de Lyon · FRDélégation Paris 5 · FRHôpital Pasteur · FR

Funding

Agence Nationale de la Recherche ANR-16-LCV1-0003-01
6 · The paper itself

Abstract

backgroundWhilst there are a number of publications comparing the relationship between body mass index (BMI) of kidney transplant recipients and graft/patient survival, no study has assessed this for a French patient cohort.

methodsIn this study, cause-specific Cox models were used to study patient and graft survival and several other time-to-event measures. Logistic regressions were performed to study surgical complications at 30 days post-transplantation as well as delayed graft function.

resultsAmong the 4691 included patients, 747 patients were considered obese with a BMI level greater than 30 kg/m

conclusionsWe showed that obesity increased the risk of death and serious bacterial infections and cardiac complications in obese French kidney transplant recipients. Further epidemiologic studies aiming to compare obese recipients versus obese candidates remaining on dialysis are needed to improve the guidelines for obese patient transplant allocation.

Indexed as

Kidney TransplantationAdultAgedCohort StudiesFemaleFranceGraft SurvivalHumansKidney Failure, ChronicMaleMiddle AgedObesityTreatment OutcomeCohort studyKidney transplantationObesityPost-transplant outcomes

Identifiers

PMID33673808
PMCPMC7934368
OpenAlexW3135476567

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.