Evidence map›Paper›PMID 33675345›Full record

ArticleThe American journal of clinical nutrition2021

Energy and macronutrient intakes at breakfast and cognitive declines in community-dwelling older adults: a 9-year follow-up cohort study.

Xianwen Shang, Edward Hill, Yanping Li, Mingguang He

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Xianwen ShangDepartment of Ophthalmology, Guandong Eye Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Edward HillDepartment of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.
Yanping LiDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-0412-2748
Mingguang HeDepartment of Ophthalmology, Guandong Eye Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Harvard University · USSun Yat-sen University · CNThe Royal Melbourne Hospital · AUUniversity of Tasmania · AU

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
MONITORING SOCIAL CHANGE: HEALTH, REPRODUCTION, AGINGR01HD030880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAIR, LINDA S, POPKIN, BARRY M · 1994 to 2024
$27.0M
POPULATION STUDIEST32HD007168 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELIZABETH A FRANKENBERG · 1985 to 2026
$13.8M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
CHILD HEALTH EFFECTS OF RAPID SOCIO-DEMOGRAPHIC CHANGER01HD038700 · NICHD · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI POPKIN, BARRY M · 2000 to 2004
$1.5M
Nutrition-Related NCD Prevention Training in ChinaD43TW009077 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI POPKIN, BARRY M · 2011 to 2015
$1.1M
Nutrition-Related NCD Prevention Training in ChinaD43TW007709 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI POPKIN, BARRY M · 2006 to 2010
$723k
FIC NIH HHS D43 TW007709FIC NIH HHS D43 TW009077NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD030880NICHD NIH HHS R01 HD038700NICHD NIH HHS R24 HD050924NICHD NIH HHS T32 HD007168NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

backgroundIt is unclear whether breakfast consumption and breakfast composition are independently associated with changes in cognition over a long-term period in older adults.

objectivesWe aimed to examine the associations between energy and macronutrient intakes at breakfast and cognitive declines.

methodsWe included 2935 participants aged 55-93 y at baseline from the China Health and Nutrition Survey in our analysis. Cognition was assessed in 1997, 2000, 2004, 2006, and 2015. Dietary intake was assessed using weighing methods in combination with 24-h food records.

resultsBreakfast contributed to 25.9% of total energy intake of the day and percentages of breakfast energy intake from protein, fat, and carbohydrates were 12.8%, 11.5%, and 75.7%, respectively. During a median follow-up of 9 y, the β values for changes in global cognitive z-scores for Quintile 5 of protein and fat intakes at breakfast, with Quintile 1 as the reference, were 0.13 (95% CI: 0.01-0.25) and 0.17 (95% CI: 0.04-0.30), respectively. Substitution of 5% energy from carbohydrates with equivalent energy from protein (β, 0.06; 95% CI: 0.01-0.11) or fat (β, 0.05; 95% CI: 0.02-0.08) at breakfast was positively associated with the change in the global cognitive z-score. Energy intake at breakfast was not significantly associated with the global cognitive z-score. Similar results were found for the verbal memory z-score. The positive association of breakfast fat intake and the inverse association of breakfast carbohydrate intake with cognitive declines were stronger in urban residents.

conclusionsHigher intakes of protein and fat and lower intake of carbohydrates at breakfast were associated with a lower rate of cognitive decline in older adults. Substitution of carbohydrates with protein or fat intake at breakfast may help to delay or prevent cognitive declines.

Indexed as

AgingBreakfastCognitive DysfunctionIndependent LivingAgedCohort StudiesDietary CarbohydratesDietary FatsDietary ProteinsFemaleHumansMaleMiddle AgedNutritional StatusNutritive ValueDietary CarbohydratesDietary FatsDietary Proteinsbreakfastcognitive declinedietary carbohydratesdietary fatdietary proteinenergy

Identifiers

PMID33675345
PMCPMC8106757
OpenAlexW3134679438

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.