Evidence map›Paper›PMID 33676415›Full record

ArticleBMC genomics2021

The complete chloroplast genome of Stauntonia chinensis and compared analysis revealed adaptive evolution of subfamily Lardizabaloideae species in China.

Feng Wen, Xiaozhu Wu, Tongjian Li, Mingliang Jia, Xinsheng Liu, Liang Liao

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 81 citations in OpenAlex.

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  3. Phylogenomic insights from the complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2026
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  9. Complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2025
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  10. The first complete chloroplast genome and phylogenetic analysis ofMitochondrial DNA. Part B, Resources · 2025
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  16. Comparative plastomes sheds light on phylogeny ofFrontiers in plant science · 2024
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Feng Wen *School of Pharmacy and Life Science, Jiujiang University, Jiujiang, China. wenfeng332@126.com.
Xiaozhu Wu *School of Pharmacy and Life Science, Jiujiang University, Jiujiang, China.
Tongjian LiSchool of Pharmacy and Life Science, Jiujiang University, Jiujiang, China.
Mingliang JiaSchool of Pharmacy and Life Science, Jiujiang University, Jiujiang, China.
Xinsheng LiuSchool of Pharmacy and Life Science, Jiujiang University, Jiujiang, China.
Liang LiaoSchool of Pharmacy and Life Science, Jiujiang University, Jiujiang, China.
Jiujiang University · CNFujian Agriculture and Forestry University · CN

Funding

Foundation of Chinese medicine research of health and family planning commission of Jiangxi province 2017B070National Natural Science Foundation of China 31560075National Natural Science Foundation of China 31760047National Natural Science Foundation of China 31960041Natural Science Foundation of Jiangxi Province 20202BABL203045
6 · The paper itself

Abstract

backgroundStauntonia chinensis DC. belongs to subfamily Lardizabaloideae, which is widely grown throughout southern China. It has been used as a traditional herbal medicinal plant, which could synthesize a number of triterpenoid saponins with anticancer and anti-inflammatory activities. However, the wild resources of this species and its relatives were threatened by over-exploitation before the genetic diversity and evolutionary analysis were uncovered. Thus, the complete chloroplast genome sequences of Stauntonia chinensis and comparative analysis of chloroplast genomes of Lardizabaloideae species are necessary and crucial to understand the plastome evolution of this subfamily.

resultsA series of analyses including genome structure, GC content, repeat structure, SSR component, nucleotide diversity and codon usage were performed by comparing chloroplast genomes of Stauntonia chinensis and its relatives. Although the chloroplast genomes of eight Lardizabaloideae plants were evolutionary conserved, the comparative analysis also showed several variation hotspots, which were considered as highly variable regions. Additionally, pairwise Ka/Ks analysis showed that most of the chloroplast genes of Lardizabaloideae species underwent purifying selection, whereas 25 chloroplast protein coding genes were identified with positive selection in this subfamily species by using branch-site model. Bayesian and ML phylogeny on CCG (complete chloroplast genome) and CDs (coding DNA sequences) produced a well-resolved phylogeny of Lardizabaloideae plastid lineages.

conclusionsThis study enhanced the understanding of the evolution of Lardizabaloideae and its relatives. All the obtained genetic resources will facilitate future studies in DNA barcode, species discrimination, the intraspecific and interspecific variability and the phylogenetic relationships of subfamily Lardizabaloideae.

Indexed as

Genome, ChloroplastBayes TheoremChinaEvolution, MolecularPhylogenyAdaptationHerbal medicinePhylogeny analysesPlastomePositive selection

Identifiers

PMID33676415
PMCPMC7937279
OpenAlexW3134651483

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.