Evidence map›Paper›PMID 33679452›Full record

ReviewFrontiers in physiology2021

TFEB: A Emerging Regulator in Lipid Homeostasis for Atherosclerosis.

Manman Li, Zitong Wang, Pengyu Wang, Hong Li, Liming Yang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  18. Frontiers in immunology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Manman LiDepartment of Pathophysiology, School of Basic Medical Sciences, Harbin Medical University, Harbin, China.
Zitong WangDepartment of Pathophysiology, School of Basic Medical Sciences, Harbin Medical University, Harbin, China.
Pengyu WangDepartment of Pathophysiology, School of Basic Medical Sciences, Harbin Medical University, Harbin, China.
Hong LiDepartment of Pathophysiology, School of Basic Medical Sciences, Harbin Medical University, Harbin, China.
Liming YangDepartment of Pathophysiology, Harbin Medical University-Daqing, Daqing, China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis, predominantly characterized by the disturbance of lipid homeostasis, has become the main causation of various cardiovascular diseases. Therefore, there is an urgent requirement to explore efficacious targets that act as lipid modulators for atherosclerosis. Transcription factor EB (TFEB), whose activity depends on post-translational modifications, such as phosphorylation, acetylation, SUMOylation, ubiquitination, etc., is significant for normal cell physiology. Recently, increasing evidence implicates a role of TFEB in lipid homeostasis,

Indexed as

atherosclerosislipid homeostasislipid mediatorslipid transporterslipophagypost-translational modificationsTFEB

Identifiers

PMID33679452
PMCPMC7925399
OpenAlexW3130515704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.