ReviewFrontiers in immunology2021
Immunomodulatory Function of Vitamin D and Its Role in Autoimmune Thyroid Disease.
Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 3 syntheses or guidelines pooled it, 181 citations in OpenAlex.
- Serum 25-hydroxyvitamin D levels are associated with thyroid diseases: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Pooled it
- Association of variant vitamin statuses and tuberculosis development: a systematic review and meta-analysis.Annals of medicine · 2024Pooled it
- Association between serum 25-hydroxyvitamin D levels and thyroid hormone profiles in Graves' disease: a retrospective cross-sectional stratified analysis.Nuclear medicine communications · 2026Article
- Clinical and Biochemical Predictors of Thyroid Autoantibody Levels in Hashimoto's Thyroiditis.Cureus · 2026Article
- Article
- The role of nutrition on thyroid health and disease: myths and facts.Journal of endocrinological investigation · 2026Review
- Comparative effectiveness of low-dose versus high-dose vitamin D on bone metabolic markers in preterm infants: a retrospective cohort study.Translational pediatrics · 2026Article
- The association between vitamin D and hypothyroidism: a systematic review and meta-analysis.Nutrition & metabolism · 2026Review
- Article
- Risk of Functional Disorders and/or Thyroid Autoimmunity and Its Association with 25OH Vitamin D and Magnesium Levels: A Population-Based Case-Control Study.Medical sciences (Basel, Switzerland) · 2026Article
- Angiogenesis, Inflammation, and Oxidative Stress: Interrelationships in Autoimmune Thyroid Diseases.International journal of molecular sciences · 2026Article
- Vitamin D and gut microbiota in thyroid diseases: mechanisms and therapeutic potential.Frontiers in immunology · 2026Review
- The therapeutic potential of vitamins as nutrients in food for anti-inflammatory and anti-oxidative stress in liver fibrosis diseases.Frontiers in nutrition · 2026Review
- Vitamin D as a central modulator of thyroid diseases: mechanisms and clinical implications.Frontiers in immunology · 2026Review
- Type 1 Diabetes and Other Autoimmune Diseases-Epidemiology, Pathophysiology and Screening.Endocrinology, diabetes & metabolism · 2026Review
- Immunosenescence in Idiopathic Pulmonary Fibrosis.Journal of inflammation research · 2026Review
- Integrative Analysis of Vitamin D-Associated Genetic Variants Reveals Cis-Regulatory Architecture and Multigenic Mechanisms Underlying Chronic Disease-Relevant Pathways.Human mutation · 2026Article
- Article
- Modulation of Peripheral Immune Cells Following Vitamin DNutrients · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D is one of the most important nutrients required by the human body. It is a steroid hormone that plays an important role in regulating calcium and phosphorus metabolism, and bone health. Epidemiological studies have revealed a close correlation between vitamin D and many common chronic diseases. Additionally, vitamin D has recently been shown to act as an immunomodulatory hormone, and, accordingly, vitamin D deficiency was uncovered as a risk factor for autoimmune thyroid diseases, although the underlying mechanisms are still unknown. It is therefore necessary to disclose the role and mechanism of action of vitamin D in the occurrence and development of autoimmune thyroid diseases. This knowledge will help design intervention and early treatment strategies for patients with autoimmune thyroid diseases who present with low levels of vitamin D.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.