Evidence map›Paper›PMID 33679802›Full record

ReviewFrontiers in immunology2021

B-Cells and Antibodies as Contributors to Effector Immune Responses in Tuberculosis.

Willemijn F Rijnink, Tom H M Ottenhoff, Simone A Joosten

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 101 citations in OpenAlex.

  1. Trial
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  6. Novel genetic variants in tuberculosis-associated immune reconstitution inflammatory syndrome.American journal of respiratory and critical care medicine · 2026
    Article
  7. Review
  8. HowVaccines · 2026
    Review
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  11. Review
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Willemijn F RijninkDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Tom H M OttenhoffDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Simone A JoostenDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NL

Funding

HLA-E restricted T-cell immunity in Mycobacterium tuberculosis infectionR01AI141315 · NIAID · LEIDEN UNIVERSITY MEDICAL CENTER · PI JOOSTEN, SIMONE ANNE · 2019 to 2022
$1.7M
In depth characterization of Mtb specific HLA-E restricted human CD8+ T-cellsR21AI127133 · NIAID · LEIDEN UNIVERSITY MEDICAL CENTER · PI OTTENHOFF, TOM · 2016 to 2017
$281k
NIAID NIH HHS R01 AI141315NIAID NIH HHS R21 AI127133
6 · The paper itself

Abstract

Tuberculosis (TB), caused by

Indexed as

AnimalsAntibodies, BacterialB-LymphocytesHumansImmunity, HumoralTuberculosisTuberculosis VaccinesAntibodies, BacterialTuberculosis VaccinesantibodiesB-cellsbiomarkerhumoral immunityMycobacterium tuberculosistuberculosis

Identifiers

PMID33679802
PMCPMC7930078
OpenAlexW3130089603

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.