Evidence map›Paper›PMID 33685340›Full record

ArticleRenal failure2021

Association between atherosclerotic cardiovascular diseases risk and renal outcome in patients with type 2 diabetes mellitus.

Honghong Ren, Lijun Zhao, Yutong Zou, Yiting Wang, Junlin Zhang, Yucheng Wu, Rui Zhang, Tingli Wang, Jiali Wang, Yitao Zhu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Honghong RenDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Lijun ZhaoDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-7750-1864
Yutong ZouDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Yiting WangDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Junlin ZhangDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Yucheng WuDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Rui ZhangDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Tingli WangDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Jiali WangDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Yitao ZhuDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Ruikun GuoDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.
Huan XuDivision of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Lin LiDivision of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Mark E CooperDepartment of Diabetes, Central Clinical School, Monash University, Melbourne, Australia.
Fang LiuDivision of Nephrology, West China Hospital of Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-1121-3004
Sichuan University · CNMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsChronic kidney disease (CKD) and diabetes mellitus increase atherosclerotic cardiovascular diseases (ASCVD) risk. However, the association between renal outcome of diabetic kidney disease (DKD) and ASCVD risk is unclear.

methodsThis retrospective study enrolled 218 type 2 diabetic patients with biopsy-proven DKD, and without known cardiovascular diseases. Baseline characteristics were obtained and the 10-year ASCVD risk score was calculated using the Pooled Cohort Equation (PCE). Renal outcome was defined as progression to end-stage renal disease (ESRD). The association between ASCVD risk and renal function and outcome was analyzed with logistic regression and Cox analysis.

resultsAmong all patients, the median 10-year ASCVD risk score was 14.1%. The median of ASCVD risk score in CKD stage 1, 2, 3, and 4 was 10.9%, 12.3%, 16.5%, and 14.8%, respectively (

conclusionsDKD patients even in CKD stage 1 had comparable ASCVD risk score to patients in CKD stage 2, 3, and 4. Higher ASCVD risk indicated severe renal insufficiency, while no prognostic value of ASVCD risk for renal outcome was observed, which implied macroangiopathy and microangiopathy in patients with DKD were related, but relatively independent.

Indexed as

AtherosclerosisCardiovascular DiseasesChinaDiabetes Mellitus, Type 2Diabetic NephropathiesDisease ProgressionFemaleGlomerular Filtration RateHumansKidney Failure, ChronicLogistic ModelsMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsAtherosclerotic cardiovascular diseasesdiabetes mellitusdiabetic kidney diseaseend-stage renal disease renal biopsy

Identifiers

PMID33685340
PMCPMC7946063
OpenAlexW3112837596

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.