Evidence map›Paper›PMID 33686483›Full record

Observational studyDiabetologia2021

Marked improvements in glycaemic outcomes following insulin pump therapy initiation in people with type 1 diabetes: a nationwide observational study in Scotland.

Anita Jeyam, Fraser W Gibb, John A McKnight, Brian Kennon, Joseph E O'Reilly, Thomas M Caparrotta, Andreas Höhn, Stuart J McGurnaghan, Luke A K Blackbourn, Sara Hatam and 11 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Diabetologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Observational
  2. Predictors of impaired awareness of hypoglycaemia and severe hypoglycaemia in adults with type 1 diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2025
    Article
  3. Dynamics and determinants of long-term quality of life in children and adolescents with type 1 diabetes: real-world evidence from China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  4. Survey of Diabetes Technology in the Pediatric Inpatient Setting.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Recent advances in oral insulin delivery technologies.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Article
  12. Article
  13. Article
  14. Observational
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 1 country.

Anita JeyamMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK. anita.jeyam@igmm.ed.ac.uk.
Fraser W GibbRoyal Infirmary of Edinburgh, Edinburgh Centre for Endocrinology and Diabetes, Edinburgh, UK.
John A McKnightWestern General Hospital, NHS Lothian, Edinburgh, UK.
Brian KennonQueen Elizabeth University Hospital, Glasgow, UK.
Joseph E O'ReillyMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Thomas M CaparrottaMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Andreas HöhnMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Stuart J McGurnaghanMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Luke A K BlackbournMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Sara HatamMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Rory J McCrimmonDivision of Molecular and Clinical Medicine, University of Dundee, Dundee, UK.
Graham LeeseNinewells Hospital, Dundee, UK.
Robert S LindsayInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
John PetrieInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
John ChalmersDiabetes Centre, Victoria Hospital, Kirkcaldy, UK.
Sam PhilipGrampian Diabetes Research Unit, Diabetes Centre, Aberdeen Royal Infirmary, Aberdeen, UK.
Sarah H WildUsher Institute of Population Health Sciences and Informatics, Centre for Population Health Sciences, School of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Edinburgh, UK.
Naveed SattarInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Paul M McKeigueUsher Institute of Population Health Sciences and Informatics, Centre for Population Health Sciences, School of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Edinburgh, UK.
Helen M ColhounMRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Scottish Diabetes Research Network (SDRN) Epidemiology Group
MRC Institute of Genetics and Molecular Medicine · GBUniversity of Edinburgh · GBUniversity of Glasgow · GBGlasgow Centre for Population Health · GBAberdeen Royal Infirmary · GBEdinburgh Royal Infirmary · GBNinewells Hospital · GBQueen Elizabeth University Hospital · GBUniversity of Dundee · GBVictoria Hospital · GBWestern General Hospital · GB

Funding

Chief Scientist Office ETM/47
6 · The paper itself

Abstract

aims/hypothesisOur aim was to assess the use of continuous subcutaneous insulin infusion (CSII) in people with type 1 diabetes in Scotland and its association with glycaemic control, as measured by HbA

methodsWe included 4684 individuals with type 1 diabetes from the national Scottish register, who commenced CSII between 2004 and 2019. We presented crude within-person differences from baseline HbA

resultsHbA CONCLUSIONS/

interpretationCSII therapy was associated with marked falls in HbA

Indexed as

Blood GlucoseGlycemic ControlAdolescentAdultChildDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsMaleScotlandTreatment OutcomeYoung AdultBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinDiabetes mellitus type 1HbA1cHypoglycaemiaInsulin pumpKetoacidosis

Identifiers

PMID33686483
PMCPMC8099793
OpenAlexW3135509218

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.