Evidence map›Paper›PMID 33686961›Full record

ArticleAging2021

Silencing SIX1 by miR-7160 inhibits non-small cell lung cancer cell growth.

Hua-Si Zhao, Xiao-Min Tao, Qun Wang, Yuan-Yuan Fang, Hong-Yu Zhang, Hua-Qi Wang, Guo-Jun Zhang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hua-Si ZhaoDepartment of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiao-Min TaoObstetrics and Gynecology Department, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Qun WangDepartment of Respiratory Medicine, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.
Yuan-Yuan FangDepartment of Endocrinology, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University, Zhengzhou, China.
Hong-Yu ZhangDepartment of Infectious Disease, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Hua-Qi WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Guo-Jun ZhangDepartment of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CNSoochow University · CNZhengzhou University · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The homeoprotein SIX1 is upregulated in non-small cell lung cancer (NSCLC) and associated with NSCLC tumorigenesis and progression. We identified microRNA-7160 (miR-7160) as a SIX1-targeting miRNA. RNA immunoprecipitation results confirmed a direct binding between miR-7160 and

Indexed as

AnimalsCarcinoma, Non-Small-Cell LungGene Expression Regulation, NeoplasticHeterograftsHomeodomain ProteinsHumansLung NeoplasmsMaleMiceMicroRNAsMiddle AgedHomeodomain ProteinsMicroRNAsSIX1 protein, humancancer growthmiR-7160NSCLCSIX1

Identifiers

PMID33686961
PMCPMC8034971
OpenAlexW3134433411

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.