Evidence map›Paper›PMID 33690845›Full record

ArticlePain medicine (Malden, Mass.)2021

Implementation of Individualized Pain Care Plans Decreases Length of Stay and Hospital Admission Rates for High Utilizing Adults with Sickle Cell Disease.

Jena L Welch-Coltrane, Anthony A Wachnik, Meredith C B Adams, Cherie R Avants, Howard A Blumstein, Amber K Brooks, Andrew M Farland, Joshua B Johnson, Manoj Pariyadath, Erik C Summers and 1 more

Open access · greenAbstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. A Qualitative Study of the Effects of Opioids on Chronic Pain, Function, and Cognition in Community-Dwelling Older Adults.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
    Article
  4. Article
  5. Beyond IV push: alternative methods for management of acute pain in SCD.Hematology. American Society of Hematology. Education Program · 2024
    Review
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jena L Welch-ColtraneDepartment of Anesthesiology, Section of Pain Medicine, Wake Forest School of Medicine, North Carolina, USA.
Anthony A WachnikDepartment of Anesthesiology, Section of Pain Medicine, Wake Forest School of Medicine, North Carolina, USA.
Meredith C B AdamsDepartment of Anesthesiology, Section of Pain Medicine, Wake Forest School of Medicine, North Carolina, USA.
Cherie R AvantsDepartment of Anesthesiology, Section of Pain Medicine, Wake Forest School of Medicine, North Carolina, USA.
Howard A BlumsteinDepartment of Emergency Medicine, Wake Forest School of Medicine, North Carolina, USA.
Amber K BrooksDepartment of Anesthesiology, Section of Pain Medicine, Wake Forest School of Medicine, North Carolina, USA.ORCID 0000-0001-9568-1336
Andrew M FarlandDepartment of Hematology, Wake Forest School of Medicine, North Carolina, USA.
Joshua B JohnsonDepartment of Internal Medicine Section of Hospital Medicine, Wake Forest University School of Medicine, North Carolina, USA.
Manoj PariyadathDepartment of Emergency Medicine, Wake Forest School of Medicine, North Carolina, USA.
Erik C SummersDepartment of Internal Medicine Section of Hospital Medicine, Wake Forest University School of Medicine, North Carolina, USA.
Robert W HurleyDepartment of Anesthesiology, Section of Pain Medicine, Wake Forest School of Medicine, North Carolina, USA.ORCID 0000-0001-6591-9390
Wake Forest University · US

Funding

Wake Forest Clinical and Translational Science AwardKL2TR001421 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, DAVID P · 2015 to 2023
$5.8M
Nudging Primary Care Providers toward Guideline-Recommended Opioid Prescribing through Easier and More Convenient EHR Information DesignR33DA046085 · NIDA · INDIANA UNIVERSITY INDIANAPOLIS · PI HARLE, CHRISTOPHER ALBERT, MAZURENKO, OLENA · 2019 to 2021
$1.7M
University of Pittsburgh Hub and Spoke Pain Clinical Trial NetworkU24NS115708 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALTER, BENEDICT J, WASAN, AJAY D · 2019 to 2024
$1.2M
Identifying opioid response phenotypes in low back pain electronic health dataK08EB022631 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ADAMS, MEREDITH C. B. · 2017 to 2020
$737k
NCATS NIH HHS KL2 TR001421NIAMS NIH HHS L30 AR074165NIBIB NIH HHS K08 EB022631NIDA NIH HHS R33 DA046085NINDS NIH HHS U24 NS115708
6 · The paper itself

Abstract

objectivePatients with sickle cell disease (SCD) face inconsistent effective analgesic management, leading to high inpatient healthcare utilization and significant financial burden for healthcare institutions. Current evidence does not provide guidance for inpatient management of acute pain in adults with sickle cell disease. We conducted a retrospective analysis of a longitudinal cohort quality improvement project to characterize the role of individualized care plans on improving patient care and reducing financial burden in high healthcare-utilizing patients with SCD-related pain.

methodsIndividualized care plans were developed for patients with hospital admissions resulting from pain associated with sickle cell disease. A 2-year prospective longitudinal cohort quality improvement project was performed and retrospectively analyzed. Primary outcome measure was duration of hospitalization. Secondary outcome measures included: pain intensity; 7, 30, and 90-day readmission rates; cost per day; total admissions; total cost per year; analgesic regimen at index admission; and discharge disposition.

resultsDuration of hospitalization, the primary outcome, significantly decreased by 1.23 days with no worsening of pain intensity scores. Seven-day readmission decreased by 34%. Use of intravenous hydromorphone significantly decreased by 25%. The potential cost saving was $1,398,827 as a result of this quality initiative.

conclusionsImplementation of individualized care plans reduced both admission rate and financial burden of high utilizing patients. Importantly, pain outcomes were not diminished. Results suggest that individualized care plans are a promising strategy for managing acute pain crisis in adult sickle cell patients from both care-focused and utilization outcomes.

Indexed as

Acute PainAnemia, Sickle CellAdultHospitalsHumansLength of StayProspective StudiesRetrospective StudiesAdmissionLOSPainSickle CellUtilization

Identifiers

PMID33690845
PMCPMC8346918
OpenAlexW3134137727

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.