Evidence mapPaperPMID 33693141Full record

ArticleCirculation reports2019

12-Week Effectiveness and Safety of Low-Density Lipoprotein Cholesterol-Lowering Therapy by Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition in Patients With Familial Hypercholesterolemia and Hypercholesterolemia - Data From a Real-World Observational Study of Evolocumab in Japan.

Koutaro Yokote, Junya Ako, Kazuo Kitagawa, Hyoe Inomata, Toshihiko Sugioka, Keiko Asao, Yasuhiko Shinmura, Junichiro Shimauchi, Tamio Teramoto

Open access · diamondAbstract read
In one paragraph

Article in Circulation reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Koutaro YokoteDepartment of Endocrinology, Hematology, and Gerontology, Chiba University Graduate School of Medicine Chiba Japan.
Junya AkoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine Sagamihara Japan.
Kazuo KitagawaDepartment of Neurology, Tokyo Women's Medical University School of Medicine Tokyo Japan.
Hyoe InomataAmgen Astellas BioPharma K.K. Tokyo Japan.
Toshihiko SugiokaAmgen Astellas BioPharma K.K. Tokyo Japan.
Keiko AsaoAmgen Astellas BioPharma K.K. Tokyo Japan.
Yasuhiko ShinmuraAmgen Astellas BioPharma K.K. Tokyo Japan.
Junichiro ShimauchiAmgen Astellas BioPharma K.K. Tokyo Japan.
Tamio TeramotoTeikyo Academic Research Center, Teikyo University Tokyo Japan.
Chiba University · JPKitasato University · JPTeikyo University · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EvolocumabFamilial hypercholesterolemiaHeterozygousHomozygousPCSK9 inhibition

Identifiers

PMID33693141
PMCPMC7889485
OpenAlexW2944162935

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.