Evidence map›Paper›PMID 33693411›Full record

ArticleFrontiers in big data2020

Identifying Clinical and Genomic Features Associated With Chronic Kidney Disease.

M Megan Moreno, Travaughn C Bain, Melissa S Moreno, Katherine C Carroll, Emily R Cunningham, Zoe Ashton, Roby Poteau, Ersoy Subasi, Michael Lipkowitz, Munevver Mine Subasi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in big data, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

M Megan MorenoDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Travaughn C BainDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Melissa S MorenoDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Katherine C CarrollDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Emily R CunninghamDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Zoe AshtonDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Roby PoteauDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Ersoy SubasiDepartment of Computer Engineering and Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Michael LipkowitzDepartment of Medicine, Georgetown University Medical Center, Washington, DC, United States.
Munevver Mine SubasiDepartment of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL, United States.
Florida Institute of Technology · USGeorgetown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We apply a pattern-based classification method to identify clinical and genomic features associated with the progression of Chronic Kidney disease (CKD). We analyze the African-American Study of Chronic Kidney disease with Hypertension dataset and construct a decision-tree classification model, consisting 15 combinatorial patterns of clinical features and single nucleotide polymorphisms (SNPs), seven of which are associated with slow progression and eight with rapid progression of renal disease among African-American Study of Chronic Kidney patients. We identify four clinical features and two SNPs that can accurately predict CKD progression. Clinical and genomic features identified in our experiments may be used in a future study to develop new therapeutic interventions for CKD patients.

Indexed as

AASKchronic kidney diseaseclassificationdecision treesgenomic analysis

Identifiers

PMID33693411
PMCPMC7931938
OpenAlexW3118887136

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.