Evidence map›Paper›PMID 33707949›Full record

ArticleJournal of multidisciplinary healthcare2021

Viral Clearance Course of COVID-19 Outbreaks.

Shaher M Samrah, Abdel-Hameed Al-Mistarehi, Tariq Kewan, Sohaib M Al-Khatib, Ali M Ibnian, Randa S Samrah, Basheer Y Khassawneh

Open access · goldAbstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Prolonged viral pneumonia and high mortality in COVID-19 patients on anti-CD20 monoclonal antibody therapy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  6. Review
  7. Postacute Sequelae of SARS-CoV-2: Musculoskeletal Conditions and Pain.Physical medicine and rehabilitation clinics of North America · 2023
    Review
  8. The effect of oseltamivir use in critically ill patients with COVID-19: A multicenter propensity score-matched study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Shaher M SamrahDepartment of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0002-8811-3741
Abdel-Hameed Al-MistarehiDepartment of Public Health and Family Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-4713-8536
Tariq KewanDepartment of Internal Medicine, Cleveland Clinic, Cleveland, OH, USA.
Sohaib M Al-KhatibDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-1754-6993
Ali M IbnianDepartment of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0002-5933-9426
Randa S SamrahFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Basheer Y KhassawnehDepartment of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-2160-4498
Jordan University of Science and Technology · JOCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) viral course and behavior remain unpredictable. This study describes incubation time and viral clearance of COVID-19 hospitalized cases in Northern Jordan.

methodsAll COVID-19 confirmed cases hospitalized from March 15 to June 09, 2020, were included. Nasopharyngeal swabs were collected, and COVID-19 reverse transcription-polymerase chain reaction (RT-PCR) was performed every two days in all cases. The viral cure was defined when two negative RT-PCR tests were obtained ≥ 24 hours apart. Viral clearance time (VCT) reflects the time from the first positive nasopharyngeal swab to the first of two consecutive negative tests.

resultsIn this cohort, a total of 157 patients were included. Most cases resulted from two major outbreaks. The median incubation period was 6 days (IQR, 3-10) and ranged from 1 to 17 days. The median VCT was 13 days (IQR, 7-2) and ranged from 1 to 40 days. Symptomatic presentation and abnormal chest radiograph were predictors for a prolonged VCT (

conclusionViral cure lagged for as long as 20 days after resolution of symptoms. Continuing with social-distancing, frequent hand hygiene, and wearing facial mask remains essential and is recommended even after clinical resolution of symptoms.

Indexed as

CDCcoronavirusCOVID-19incubation periodpandemicviral clearanceviral shedding

Identifiers

PMID33707949
PMCPMC7941054
OpenAlexW3135532417

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.