Evidence map›Paper›PMID 33708483›Full record

ArticleCardiovascular diagnosis and therapy2021

Resting heart rate predicts all-cause mortality in sub-Saharan African patients with heart failure: a prospective analysis from the Douala Heart failure registry (Do-HF).

Anastase Dzudie, Blaise Barche, Sidick Mouliom, Ariane Nouko, Raissa Fogue, Jules Ndjebet, Serah Abang Makoh, Joseph Abah, Armel Djomou, Archange Nzali and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Anastase DzudieCardiology and Cardiac Pacing Unit, Douala General Hospital, Douala, Cameroon.
Blaise BarcheClinical Research Education Networking & Consultancy (CRENC), Douala, Cameroon.
Sidick MouliomCardiology and Cardiac Pacing Unit, Douala General Hospital, Douala, Cameroon.
Ariane NoukoClinical Research Education Networking & Consultancy (CRENC), Douala, Cameroon.
Raissa FogueClinical Research Education Networking & Consultancy (CRENC), Douala, Cameroon.
Jules NdjebetDouala Cardiovascular Center, Douala, Cameroon.
Serah Abang MakohMboppi Baptist Hospital, Douala, Cameroon.
Joseph AbahDouala Military Hospital, Cameroon.
Armel DjomouClinique Cœur et vie, Douala, Cameroon.
Archange NzaliClinical Research Education Networking & Consultancy (CRENC), Douala, Cameroon.
Clovis NkokeClinical Research Education Networking & Consultancy (CRENC), Douala, Cameroon.
Felicite KamdemCardiology and Cardiac Pacing Unit, Douala General Hospital, Douala, Cameroon.
Samuel KingueFaculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
Karen SliwaHatter Institute for Cardiovascular Research in Africa and the Institute of Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Andre Pascal KengneDepartment of Medicine, University of Cape Town, Cape Town, South Africa.
University of Douala · CMGeriatric Research Education and Clinical Center · USUniversity of Cape Town · ZACameroon Baptist Convention Health Services · CMYaoundé General Hospital · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigher resting heart rate (HR) is associated with mortality amongst Caucasians with heart failure (HF), but its significance has yet to be established in sub-Saharan Africans in whom HF differs in terms of characteristics and etiologies. We assessed the association of HR with all-cause mortality in patients with HF in sub-Saharan Africa.

methodsThe Douala HF registry (Do-HF) is an ongoing prospective data collection on patients with HF receiving care at four cardiac referral services in Douala, Cameroon. Patients included in this report were followed-up for 12 months from their index admission, for all-cause mortality. We used Cox-regression analysis to study the association of HR with all-cause mortality during follow-up.

resultsOf 347 patients included, 343 (98.8%) completed follow-up. The mean age was 64±14 years, 176 (50.7%) were female, and median admission HR was 85 bpm. During a median follow-up of 12 months, 78 (22.7%) patients died. Mortality increased steadily with HR increase and ranged from 12.2% in the lower quartile of HR (≤69 bpm) to 34.1% in the upper quartile of HR (>100 bpm). Hazard ratio of 12-month death per 10 bpm higher HR was 1.16 (1.04-1.29), with consistent effects across most subgroups, but a higher effect in participants with hypertension

conclusionsHR was independently associated with increased risk of all-cause mortality in this study, particularly among participants with hypertension. The implication of this finding for risk prediction or reduction should be actively investigated.

Indexed as

Africaheart failure (HF)heart rate (HR)mortalityoutcome

Identifiers

PMID33708483
PMCPMC7944210
OpenAlexW3128089843

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.