ReviewCurrent diabetes reports2021
Brain Health in Children with Type 1 Diabetes: Risk and Protective Factors.
Review in Current diabetes reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Pooled it
- Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes.Endocrinology, diabetes & metabolism · 2023Trial
- A Pilot randomized trial to examine effects of a hybrid closed-loop insulin delivery system on neurodevelopmental and cognitive outcomes in adolescents with type 1 diabetes.Nature communications · 2022Trial
- Promoting glycemic control in young children with type I diabetes: Results from a pilot intervention for parents.Families, systems & health : the journal of collaborative family healthcare · 2022Trial
- Role of the TLR4-NF-κB-FDX1 cuproptosis axis in mediating cognitive impairment associated with type 1 diabetes in children: an exploratory mechanistic study.Metabolic brain disease · 2026Article
- Ketogenic Diet in Children with Type 1 Diabetes: Parental Motivations and Potential Risks for Metabolic Health and Development.Nutrients · 2026Review
- The Impact of Diabetes on Brain Health in Childhood.Biomedicines · 2026Review
- Shared genetic and neuroimmune architecture links type 1 diabetes with neurocognitive traits.Nature communications · 2026Article
- Sleep coach intervention for adolescents with type 1 diabetes: Rationale and trial design.Contemporary clinical trials · 2025Article
- Cognitive flexibility is associated with the age of onset and duration among patients with type 1 diabetes.Scientific reports · 2025Article
- Glucose Extremes and Cognitive Function: A Review of the Neurological Impacts of Hypoglycemia and Hyperglycemia in Type 1 Diabetes.Diabetes spectrum : a publication of the American Diabetes Association · 2025Article
- Intervention to reduce barriers to type 1 diabetes self-management: Diabetes Journey study design and participant characteristics.Contemporary clinical trials · 2025Article
- Online diabetes self-management education application for reducing glycated hemoglobin level among patients with type 1 diabetes mellitus: a systematic review and meta-analysis.Clinical diabetes and endocrinology · 2024Review
- Safety and Efficacy of Using Advanced Hybrid Closed Loop Off-Label in an Infant Diagnosed with Permanent Neonatal Diabetes Mellitus: A Case Report and a Look to the Future.Children (Basel, Switzerland) · 2024Article
- Using Community Engagement Methods to Guide Study Protocol Decisions for School-Aged Children With Type 1 Diabetes.Diabetes spectrum : a publication of the American Diabetes Association · 2024Article
- Differential Cortical Volume and Surface Morphometry in Youth With Chronic Health Conditions.Biological research for nursing · 2024Article
- Cognitive disengagement syndrome in children with type 1 diabetes: important implications for clinical outcomes.Acta diabetologica · 2024Article
- The relationship between diabetic ketoacidosis and suicidal or self-injurious behaviour: A systematic review.Journal of clinical & translational endocrinology · 2023Review
- A comparative study using insulin pump therapy and continuous glucose monitoring in newly diagnosed very young children with type 1 diabetes: it is possible to bend the curve of HbA1c.Acta diabetologica · 2023Observational
- Exploratory Multisite MR Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children.AJNR. American journal of neuroradiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewTo synthesize findings from studies of neurocognitive complications in children with type 1 diabetes (T1D) and highlight potential risk and protective factors. RECENT
findingsEmerging evidence suggests that hyperglycemia and time in range may be more important for brain development than episodes of hypoglycemia. Further, diabetic ketoacidosis (DKA) at the time of T1D diagnosis appears to be a particular risk factor for neurocognitive complications, particularly deficits in executive function skills and memory, with differences in cerebral white matter microstructure seen via advanced magnetic resonance imaging methods, and lower scores on measures of attention and memory observed among children who were diagnosed in DKA. Other factors that may influence neurocognitive development include child sleep, caregiver distress, and diabetes device use, presumably due to improved glycemic control. We highlight neurocognitive risk and protective factors for children with T1D and priorities for future research in this high-risk population.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.