Evidence map›Paper›PMID 33716704›Full record

ArticleFrontiers in synaptic neuroscience2021

Multi-Electrode Array Analysis Identifies Complex Dopamine Responses and Glucose Sensing Properties of Substantia Nigra Neurons in Mouse Brain Slices.

Nadja Mannal, Katharina Kleiner, Michael Fauler, Antonios Dougalis, Christina Poetschke, Birgit Liss

Open access · goldAbstract read
In one paragraph

Article in Frontiers in synaptic neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Nadja MannalInstitute of Applied Physiology, University of Ulm, Ulm, Germany.
Katharina KleinerInstitute of Applied Physiology, University of Ulm, Ulm, Germany.
Michael FaulerInstitute of Applied Physiology, University of Ulm, Ulm, Germany.
Antonios DougalisInstitute of Applied Physiology, University of Ulm, Ulm, Germany.
Christina PoetschkeInstitute of Applied Physiology, University of Ulm, Ulm, Germany.
Birgit LissInstitute of Applied Physiology, University of Ulm, Ulm, Germany.
Universität Ulm · DETechnische Hochschule Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopaminergic (DA) midbrain neurons within the substantia nigra (SN) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. Their progressive degeneration is a hallmark of Parkinson's disease. Their metabolically demanding activity-mode affects Ca

Indexed as

dopamine-autoreceptordopamine excited neuronsdopamine inhibited neuronsdopamine receptor desensitizationGIRK channelglucose-excited GE-neuronsglucose-responsive neuronsneuronal calcium sensor NCS-1

Identifiers

PMID33716704
PMCPMC7952765
OpenAlexW3135787470

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.