Evidence map›Paper›PMID 33718593›Full record

ArticleMolecular therapy oncolytics2021

Applications of nuclear-based imaging in gene and cell therapy: probe considerations.

Alessia Volpe, Naga Vara Kishore Pillarsetty, Jason S Lewis, Vladimir Ponomarev

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Where did my vector go and how well did it function? PET biodistribution studies of viral gene therapy vectors.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  6. Recent developments in translational imaging of in vivo gene therapy outcomes.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Evaluation of [Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  11. Review
  12. Review
  13. Review
  14. Reporter Genes for Brain Imaging Using MRI, SPECT and PET.International journal of molecular sciences · 2022
    Review
  15. Review
  16. CovalentPharmaceuticals (Basel, Switzerland) · 2021
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alessia VolpeDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Naga Vara Kishore PillarsettyDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jason S LewisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Vladimir PonomarevDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Several types of gene- and cell-based therapeutics are now emerging in the cancer immunotherapy, transplantation, and regenerative medicine landscapes. Radionuclear-based imaging can be used as a molecular imaging tool for repetitive and non-invasive visualization as well as

Indexed as

cell therapygene therapynuclear imagingradiotracer

Identifiers

PMID33718593
PMCPMC7907215
OpenAlexW3127127141

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.