Evidence map›Paper›PMID 33718754›Full record

ArticleCurrent developments in nutrition2021

Ingesting Yogurt Containing

Takayuki Toshimitsu, Ayako Gotou, Toshihiro Sashihara, Keisuke Furuichi, Satoshi Hachimura, Nobuhiko Shioya, Satoru Suzuki, Yukio Asami

Open access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Role ofInternational journal of molecular sciences · 2024
    Pooled it
  4. Pooled it
  5. Effects ofNutrients · 2022
    Trial
  6. Efficacy and Safety ofFrontiers in endocrinology · 2021
    Trial
  7. Review
  8. Review
  9. Food science & nutrition · 2025
    Article
  10. Review
  11. Article
  12. Microorganisms · 2024
    Review
  13. Nutrients · 2023
    Article
  14. Article
  15. Review
  16. Bile acids, gut microbiota and metabolic surgery.Frontiers in endocrinology · 2022
    Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Takayuki ToshimitsuApplied Microbiology Research Department, Food Microbiology Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Hachiouji, Tokyo, Japan.ORCID 0000-0003-0506-4743
Ayako GotouApplied Microbiology Research Department, Food Microbiology Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Hachiouji, Tokyo, Japan.
Toshihiro SashiharaApplied Microbiology Research Department, Food Microbiology Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Hachiouji, Tokyo, Japan.ORCID 0000-0001-7617-0987
Keisuke FuruichiApplied Microbiology Research Department, Food Microbiology Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Hachiouji, Tokyo, Japan.
Satoshi HachimuraResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Nobuhiko ShioyaStatistical Analysis Department, KSO Corporation, Minato-ku, Tokyo, Japan.
Satoru SuzukiShinagawa Season Terrace Health Care Clinic, Minato-ku, Tokyo, Japan.
Yukio AsamiApplied Microbiology Research Department, Food Microbiology Research Laboratories, Division of Research and Development, Meiji Co., Ltd., Hachiouji, Tokyo, Japan.
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic inflammation and insulin resistance are factors that are related to obesity. We have suggested that the administration of heat-treated

objectiveThe aim of this study was to investigate whether ingesting OLL2712 cells can reduce body fat accumulation and improve metabolic risk factors, in overweight, healthy adults.

methodsThis study was a randomized, double-blind, placebo-controlled, parallel-group trial conducted at a single center in Japan. The study participants included 100 overweight (BMI range, ≥25 to <30 kg/m

resultsThe 12-wk change of abdominal fat area (difference: 8.5 cm

conclusionsThe ingestion of heat-treated OLL2712 cells reduces body fat accumulation and the deterioration of glycemic control and chronic inflammation, in overweight, healthy adults. We hypothesize that OLL2712 cells may prevent obesity by regulating chronic inflammation. This trial was registered at the University Hospital Medical Information Network Clinical Trials Registry as UMIN000027709.

Indexed as

abdominal fat areachronic inflammationfasting plasma glucosehigh-sensitivity C-reactive proteinHOMA-IRinsulin resistanceinterleukin-6Lactobacillus plantarumyogurt

Identifiers

PMID33718754
PMCPMC7937491
OpenAlexW3127692232

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.