ArticleEuropean journal of applied physiology2021
Sprint interval training (SIT) reduces serum epidermal growth factor (EGF), but not other inflammatory cytokines in trained older men.
Article in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- High-Intensity Interval Training (HIIT) in Hypoxia Improves Maximal Aerobic Capacity More Than HIIT in Normoxia: A Systematic Review, Meta-Analysis, and Meta-Regression.International journal of environmental research and public health · 2022Pooled it
- Effects of Exercise Training on Anabolic and Catabolic Hormones with Advanced Age: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Association of postoperative delirium with serum and cerebrospinal fluid proteomic profiles: a prospective cohort study in older hip fracture patients.GeroScience · 2024Article
- Three-week sprint interval training (SIT) reduces cell-free DNA and low-frequency fatigue but does not induce VO2max improvement in older men.European journal of applied physiology · 2024Article
- Regional and time course differences in sweat cortisol, glucose, and select cytokine concentrations during exercise.European journal of applied physiology · 2023Article
- Aerobically trained older adults show impaired resting, but preserved exercise-induced circulating progenitor cell count, which was not improved by sprint interval training.Pflugers Archiv : European journal of physiology · 2023Article
- Targeted Lipidomics and Inflammation Response to Six Weeks of Sprint Interval Training in Male Adolescents.International journal of environmental research and public health · 2023Article
- The effect of exercise on blood concentrations of angiogenesis markers in older adults: a systematic review and meta-analysis.Research square · 2023Article
- A pilot study: the relationship between salivary MCP-1 and IgA, and exercise performance in long-distance runners and sprinters.BMC research notes · 2022Article
- Short-Term and Lifelong Exercise Training Lowers Inflammatory Mediators in Older Men.Frontiers in physiology · 2021Article
- High Intensity Interval Training (HIIT) as a Potential Countermeasure for Phenotypic Characteristics of Sarcopenia: A Scoping Review.Frontiers in physiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study aimed to investigate the effect of age on circulating pro- and anti-inflammatory cytokines and growth factors. A secondary aim was to investigate whether a novel sprint interval training (SIT) intervention (3 × 20 s 'all out' static sprints, twice a week for 8 weeks) would affect inflammatory markers in older men.
methodsNine older men [68 (1) years] and eleven younger men [28 (2) years] comprised the younger group. Aerobic fitness and inflammatory markers were taken at baseline for both groups and following the SIT intervention for the older group.
resultsInterleukin (IL)-8, vascular endothelial growth factor (VEGF), and monocyte chemoattractant protein-1 (MCP-1) were unchanged for the older and younger groups at baseline (IL-8, p = 0.819; MCP-1, p = 0.248; VEGF, p = 0.264). Epidermal growth factor (EGF) was greater in the older group compared to the younger group at baseline [142 (20) pg mL
conclusionOlder aerobically trained men have greater serum EGF than younger aerobically trained men. A novel SIT intervention in older men can shift circulating EGF towards trained younger concentrations. As lower EGF has previously been associated with longevity in C. elegans, the manipulative effect of SIT on EGF in healthy ageing in the human may be of further interest.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.