Evidence mapPaperPMID 33729661Full record

ArticleDiabetes, obesity & metabolism2021

The burden of poor glycaemic control in people with newly diagnosed type 2 diabetes in Sweden: A health economic modelling analysis based on nationwide data.

Margareta Hellgren, Ann-Marie Svensson, Stefan Franzén, Åsa Ericsson, Soffia Gudbjörnsdottir, Nils Ekström, Rebecka Bertilsson, William Valentine, Samuel Malkin

Abstract read
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Article in Diabetes, obesity & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  10. Disease and Economic Burden of Poor Metabolic and Weight Control in Type 2 Diabetes in Spain: A Systematic Literature Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  11. Article
  12. Review
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  14. Assessing the Effectiveness of Type 2 Diabetes Screening in the Republic of Uzbekistan.International journal of endocrinology and metabolism · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Margareta HellgrenThe Skaraborg Institute, Skövde, Sweden.
Ann-Marie SvenssonThe Swedish National Diabetes Register, Västra Götalandsregionen, Gothenburg, Sweden.
Stefan FranzénRegister Centrum Västra Götaland, Göteborg, Sweden.
Åsa EricssonNovo Nordisk Scandinavia AB, Malmö, Sweden.
Soffia GudbjörnsdottirThe Swedish National Diabetes Register, Västra Götalandsregionen, Gothenburg, Sweden.
Nils EkströmNovo Nordisk Scandinavia AB, Malmö, Sweden.
Rebecka BertilssonRegister Centrum Västra Götaland, Göteborg, Sweden.
William ValentineOssian Health Economics and Communications, Basel, Switzerland.
Samuel MalkinOssian Health Economics and Communications, Basel, Switzerland.ORCID 0000-0003-1306-7784

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the economic and clinical burden associated with poor glycaemic control in Sweden, in people with type 2 diabetes (T2D) initiating first-line glucose-lowering therapy. MATERIALS AND

methodsPopulation data were obtained from Swedish national registers. Immediate glycaemic control was compared with delays in achieving control of 1 and 3 years, with outcomes projected over 3, 10 and 50 years in the validated IQVIA CORE Diabetes Model. Glycaemic control was defined as glycated haemoglobin (HbA1c) targets of 52, 48 and 42 mmol/mol, as recommended in Swedish guidelines, according to age and disease duration. Costs (expressed in 2019 Swedish krona [SEK]) were accounted from a Swedish societal perspective.

resultsImmediate glycaemic control was associated with population-level cost savings of up to SEK 279 million and SEK 673 million versus delays of 1 and 3 years, respectively, as well as small population-level life expectancy benefits of up to 1305 and 2590 life years gained. Reduced levels of burden were a result of lower incidence and delayed time to onset of diabetes-related complications.

conclusionsEven in people with T2D initiating first-line glucose-lowering therapy, the economic burden of poor glycaemic control in Sweden is substantial, but could be reduced by early and effective treatment to achieve glycaemic targets.

Indexed as

Diabetes Mellitus, Type 2Blood GlucoseGlycated HemoglobinGlycemic ControlHumansHypoglycemic AgentsSwedenBlood GlucoseGlycated HemoglobinHypoglycemic Agentsdiabetes complicationsglycaemic controlhealth economicstype 2 diabetes

Identifiers

PMID33729661
PMCPMC8360155

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.