Evidence map›Paper›PMID 33730790›Full record

ArticleEnvironmental analysis, health and toxicology2021

Developmental toxicity of cadmium in infants and children: a review.

Lalit Chandravanshi, Kunal Shiv, Sudhir Kumar

Open access · hybridAbstract read
In one paragraph

Article in Environmental analysis, health and toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Overview of Ferroptosis in Cadmium Toxicity.Biological trace element research · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Four Decades of Environmental Analysis, Health and Toxicology.Environmental analysis, health and toxicology · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Lalit ChandravanshiDepartment of Forensic Science, College and Traffic Management- Institute of Road and Traffic Education, Faridabad - Haryana - 121010, India.
Kunal ShivDivision of Forensic Science, School of Basic & Applied Sciences, Galgotias University Greater Noida - 201306, India.
Sudhir KumarForensic Science laboratory, Modinagar, Ghaziabad - 201204, India.
Central Forensic Science Laboratory · INESIC Hospital · INGalgotias University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several millions of people are exposed to cadmium worldwide due to natural and anthropogenic activities that led to their widespread distribution in the environment and have shown potential adverse effects on the kidneys, liver, heart and nervous system. Recently human and animal-based studies have been shown that In utero and early life exposure to cadmium can have serious health issues that are related to the risk of developmental disabilities and other outcomes in adulthood. Since, cadmium crosses the placental barrier and reaches easily to the fetus, even moderate or high-level exposure of this metal during pregnancy could be of serious health consequences which might be reflected either in the children's early or later stages of life. Mortality from various diseases including cancer, cardiovascular, respiratory, kidney and neurological problems, correlation with In utero or early life exposure to cadmium has been found in epidemiological studies. Animal studies with strong evidence of various diseases mostly support for the human studies, as well as suggested a myriad mechanism by which cadmium can interfere with human health and development. More studies are needed to establish the mechanism of cadmium-induced toxicity with environmentally relevant doses in childhood and later life. In this review, we provide a comprehensive examination of the literature addressing potential long- term health issues with In utero and early life exposure to cadmium, as well as correlating with human and animal exposure studies.

Indexed as

cadmiumcognitiondevelopmental neurotoxicitykidney dysfunctions

Identifiers

PMID33730790
PMCPMC8207007
OpenAlexW3127603019

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.