ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Oscillatory Entrainment of the Frequency-following Response in Auditory Cortical and Subcortical Structures.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 53 citations in OpenAlex.
- Multisensory flicker modulates widespread brain networks and reduces interictal epileptiform discharges.Nature communications · 2024Trial
- Sleep Oscillations Across Cortical, Subcortical and Cerebellar Structures in Magnetoencephalography.The European journal of neuroscience · 2026Article
- Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Event-Related Brain Potentials and Frequency-Following Response to Syllables in Newborns and Adults.The European journal of neuroscience · 2026Article
- Temporal-oscillatory entrainment: a multi-timescale framework for rhythmic coordination from neural to social frequencies.Frontiers in human neuroscience · 2026Article
- Sleep State Influences Early Sound Encoding at Cortical But Not Subcortical Levels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Gamma entrainment induced by deep brain stimulation as a biomarker for motor improvement with neuromodulation.Nature communications · 2025Article
- The neural activity of auditory conscious perception.NeuroImage · 2025Article
- Review
- Article
- Challenges and Approaches in the Study of Neural Entrainment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Cortical-subcortical interactions underlie processing of auditory predictions measured with 7T fMRI.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cortical representation of speech temporal information through high gamma-band activity and its temporal modulation.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Assessing Auditory Processing in Children with Listening Difficulties: A Pilot Study.Journal of clinical medicine · 2023Article
- Supramodality of neural entrainment: Rhythmic visual stimulation causally enhances auditory working memory performance.Science advances · 2022Article
- Connectomics of human electrophysiology.NeuroImage · 2022Article
- On the Role of Neural Oscillations Across Timescales in Speech and Music Processing.Frontiers in computational neuroscience · 2022Review
- Resonance as a Design Strategy for AI and Social Robots.Frontiers in neurorobotics · 2022Article
- Enhanced brainstem phase-locking in low-level noise reveals stochastic resonance in the frequency-following response (FFR).Brain research · 2021Review
- Frequency Selectivity of Persistent Cortical Oscillatory Responses to Auditory Rhythmic Stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
There is much debate about the existence and function of neural oscillatory mechanisms in the auditory system. The frequency-following response (FFR) is an index of neural periodicity encoding that can provide a vehicle to study entrainment in frequency ranges relevant to speech and music processing. Criteria for entrainment include the presence of poststimulus oscillations and phase alignment between stimulus and endogenous activity. To test the hypothesis of entrainment, in experiment 1 we collected FFR data for a repeated syllable using magnetoencephalography (MEG) and electroencephalography in 20 male and female human adults. We observed significant oscillatory activity after stimulus offset in auditory cortex and subcortical auditory nuclei, consistent with entrainment. In these structures, the FFR fundamental frequency converged from a lower value over 100 ms to the stimulus frequency, consistent with phase alignment, and diverged to a lower value after offset, consistent with relaxation to a preferred frequency. In experiment 2, we tested how transitions between stimulus frequencies affected the MEG FFR to a train of tone pairs in 30 people. We found that the FFR was affected by the frequency of the preceding tone for up to 40 ms at subcortical levels, and even longer durations at cortical levels. Our results suggest that oscillatory entrainment may be an integral part of periodic sound representation throughout the auditory neuraxis. The functional role of this mechanism is unknown, but it could serve as a fine-scale temporal predictor for frequency information, enhancing stability and reducing susceptibility to degradation that could be useful in real-life noisy environments.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.