Evidence map›Paper›PMID 33732994›Full record

ArticleKidney international reports2021

Population Estimates of GFR and Risk Factors for CKD in Guatemala.

Ann C Miller, Eva Tuiz, Leah Shaw, David Flood, Pablo Garcia, Eloin Dhaenens, Dana R Thomson, Joaquin Barnoya, Carlos Mendoza Montano, Peter Rohloff

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Global health inequalities of chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala.Revista panamericana de salud publica = Pan American journal of public health · 2023
    Article
  7. Adults' Experiences with Type 2 Diabetes in Rural Guatemala: A Qualitative Study.Journal of health care for the poor and underserved · 2023
    Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Ann C MillerDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Eva TuizCentro de Investigación en la Salud Indígena, Wuqu' Kawoq, Tecpán, Guatemala.
Leah ShawCentro de Investigación en la Salud Indígena, Wuqu' Kawoq, Tecpán, Guatemala.
David FloodCentro de Investigación en la Salud Indígena, Wuqu' Kawoq, Tecpán, Guatemala.
Pablo GarciaCentro de Investigación en la Salud Indígena, Wuqu' Kawoq, Tecpán, Guatemala.
Eloin DhaenensCentro de Investigación en la Salud Indígena, Wuqu' Kawoq, Tecpán, Guatemala.
Dana R ThomsonDepartment of Social Statistics and Demography, University of Southampton, Southampton, UK.
Joaquin BarnoyaUnidad de Cirugia Cardiovascular, Guatemala City, Guatemala.
Carlos Mendoza MontanoInstituto de Nutrición de Centroamérica y Panamá, INCAP, Guatemala City, Guatemala.
Peter RohloffCentro de Investigación en la Salud Indígena, Wuqu' Kawoq, Tecpán, Guatemala.
Brigham and Women's Hospital · USHarvard University · USInstitute of Nutrition of Central America and Panama · GTUnidad de Cirugía Cardiovascular de Guatemala · GTUniversity of Southampton · GB

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Building Capacity for Chronic Kidney Disease Research in Guatemala.R21TW010831 · FIC · BRIGHAM AND WOMEN'S HOSPITAL · PI MENDOZA, CARLOS, ROHLOFF, PETER · 2017 to 2018
$335k
FIC NIH HHS R21 TW010831NIDDK NIH HHS P30 DK092926
6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) is an emerging public health priority in Central America. However, data on the prevalence of CKD in Guatemala, Central America's most populous country, are limited, especially for rural communities.

methodsWe conducted a population-representative survey of 2 rural agricultural municipalities in Guatemala. We collected anthropometric data, blood pressure, serum and urine creatinine, glycosylated hemoglobin, and urine albumin. Sociodemographic, health, and exposure data were self-reported.

resultsWe enrolled 807 individuals (63% of all eligible, 35% male, mean age 39.5 years). An estimated 4.0% (95% confidence interval [CI] 2.4-6.6) had CKD, defined as an estimated glomerular filtration rate (eGFR) less than 60 ml/min per 1.73 m

conclusionsIn this population-based survey, most observed CKD was associated with diabetes and hypertension. These results emphasize the urgent public health need to address the emerging epidemic of diabetes, hypertension, and CKD in rural Guatemala. In addition, the association between CKD and sugar cane in individuals living in poverty provides some circumstantial evidence for existence of CKD of unknown etiology in the study communities, which requires further investigation.

Indexed as

Central AmericaCKDCKD of unknown etiologyglobal health

Identifiers

PMID33732994
PMCPMC7938058
OpenAlexW3119456973

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.