Evidence map›Paper›PMID 33742610›Full record

ArticleIndian pediatrics2021

Steroid Sensitive Nephrotic Syndrome: Revised Guidelines.

Aditi Sinha, Arvind Bagga, Sushmita Banerjee, Kirtisudha Mishra, Amarjeet Mehta, Indira Agarwal, Susan Uthup, Abhijeet Saha, Om Prakash Mishra, Expert Group of Indian Society of Pediatric Nephrology

Open access · bronzeAbstract read
In one paragraph

Article in Indian pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Observational
  6. Proteinuria in adolescence.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Combined Fibrinogen and Urinary α1-Microglobulin as Predictors of Respiratory Tract Infection in Children with Nephrotic Syndrome.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  16. Varicella vaccination in children with nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Aditi SinhaDivision of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Arvind BaggaDivision of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. Correspondence to: Dr. Arvind Bagga, Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. arvindbagga@hotmail.com.
Sushmita BanerjeeDepartment of Pediatrics, Institute of Child Health, Kolkata, India.
Kirtisudha MishraDepartment of Pediatrics, Chacha Nehru Bal Chikitsalaya, Delhi, India.
Amarjeet MehtaDepartment of Pediatrics, Sawai Man Singh Medical College, Jaipur, India.
Indira AgarwalDepartment of Pediatrics, Christian Medical College, Vellore, India.
Susan UthupDepartment of Pediatrics, Trivandrum Medical College, Thiruvananthapuram, India.
Abhijeet SahaDepartment of Pediatrics, Lady Hardinge Medical College, New Delhi, India.
Om Prakash MishraDepartment of Pediatrics, Institute of Medical Sciences, Benaras Hindu University, Varanasi, India.
Expert Group of Indian Society of Pediatric Nephrology
All India Institute of Medical Sciences · INBanaras Hindu University · INChacha Nehru Bal Chikitsalaya · INChristian Medical College & Hospital · INInstitute of Child Health · INLady Hardinge Medical College · INSawai ManSingh Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

justificationSteroid sensitive nephrotic syndrome (SSNS) is one of the most common chronic kidney diseases in children. These guidelines update the existing Indian Society of Pediatric Nephrology recommendations on its management.

objectiveTo frame revised guidelines on diagnosis, evaluation, management and supportive care of patients with the illness. PROCESS: The guidelines combine evidence-based recommendations and expert opinion. Formulation of key questions was followed by review of literature and evaluation of evidence by experts in two face-to-face meetings. RECOMMENDATIONS: The initial statements provide advice for evaluation at onset and follow up and indications for kidney biopsy. Subsequent statements provide recommendations for management of the first episode of illness and of disease relapses. Recommendations on the use of immunosuppressive strategies in patients with frequent relapses and steroid dependence are accompanied by suggestions for step-wise approach and plan of monitoring. Guidance is also provided regarding the management of common complications including edema, hypovolemia and serious infections. Advice on immunization and transition of care is given. The revised guideline is intended to improve the management and outcomes of patients with SSNS, and provide directions for future research.

Indexed as

NephrologyNephrotic SyndromeChildHumansImmunosuppressive AgentsRecurrenceImmunosuppressive Agents

Identifiers

PMID33742610
PMCPMC8139225
OpenAlexW3137141132

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.