Evidence map›Paper›PMID 33746951›Full record

ReviewFrontiers in immunology2021

Perspectives on the Genetic Associations of Ankylosing Spondylitis.

B Paul Wordsworth, Carla J Cohen, Connor Davidson, Matteo Vecellio

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Observational
  2. Review
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  7. Environmental and Genetic Determinants of Ankylosing Spondylitis.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

B Paul WordsworthNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford Institute of Musculoskeletal Sciences, Oxford, United Kingdom.
Carla J CohenBotnar Research Centre, Nuffield Orthopaedic Centre, Oxford, United Kingdom.
Connor DavidsonWellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Matteo VecellioNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford Institute of Musculoskeletal Sciences, Oxford, United Kingdom.
Nuffield Orthopaedic Centre · GBUniversity of Oxford · GB

Funding

Department of Health A93081Versus Arthritis 19356Versus Arthritis 20402Versus Arthritis 20796Versus Arthritis 21428Versus Arthritis 22198
6 · The paper itself

Abstract

Ankylosing spondylitis (AS) is a common form of inflammatory spinal arthritis with a complex polygenic aetiology. Genome-wide association studies have identified more than 100 loci, including some involved in antigen presentation (

Indexed as

HLA-B27 AntigenSpondylitis, AnkylosingAntigen PresentationGenetic LociGenome-Wide Association StudyHumansMacrophagesTh17 CellsHLA-B27 Antigenaetiologyepigeneticsinterleukin-23pathogenesisspondyloarthropathy

Identifiers

PMID33746951
PMCPMC7977288
OpenAlexW3133947674

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.