Evidence map›Paper›PMID 33748281›Full record

ArticleBioMed research international2021

Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron's Connection: A Possible Neuroprotector Effect.

Gian Lucas M Arruda, Hugo Vigerelli, Michelle C Bufalo, Giovanna B Longato, Rodinei V Veloso, Vanessa O Zambelli, Gisele Picolo, Yara Cury, André C Morandini, Antonio Carlos Marques and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Gian Lucas M ArrudaLaboratório Multidisciplinar de Pesquisa, Universidade São Francisco, Bragança Paulista 12916-900, Brazil.
Hugo VigerelliLaboratório de Genética, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID https://orcid.org/0000-0002-8197-2260
Michelle C BufaloLaboratório de Dor e Sinalização, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID https://orcid.org/0000-0003-3673-1684
Giovanna B LongatoLaboratório de Pesquisa em Farmacologia Molecular e Compostos Bioativos, Universidade São Francisco, Bragança Paulista 12916-900, Brazil.ORCID https://orcid.org/0000-0001-5828-8957
Rodinei V VelosoLaboratório Multidisciplinar de Pesquisa, Universidade São Francisco, Bragança Paulista 12916-900, Brazil.
Vanessa O ZambelliLaboratório de Dor e Sinalização, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID https://orcid.org/0000-0003-0890-9561
Gisele PicoloLaboratório de Dor e Sinalização, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID https://orcid.org/0000-0001-6784-8266
Yara CuryLaboratório de Dor e Sinalização, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID https://orcid.org/0000-0002-6245-3166
André C MorandiniDepartamento de Zoologia, Instituto de Biociências, Universidade de São Paulo, São Paulo 05508-090, Brazil.ORCID https://orcid.org/0000-0003-3747-8748
Antonio Carlos MarquesDepartamento de Zoologia, Instituto de Biociências, Universidade de São Paulo, São Paulo 05508-090, Brazil.ORCID https://orcid.org/0000-0002-2884-0541
Juliana Mozer ScianiLaboratório Multidisciplinar de Pesquisa, Universidade São Francisco, Bragança Paulista 12916-900, Brazil.ORCID https://orcid.org/0000-0001-7213-206X
Instituto Butantan · BRUniversidade São Francisco · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative diseases are one of the major causes of death worldwide, characterized by neurite atrophy, neuron apoptosis, and synapse loss. No effective treatment has been indicated for such diseases so far, and the search for new drugs is being increased in the last years. Animal venoms' secretion/venom can be an alternative for the discovery of new molecules, which could be the prototype for a new treatment. Here, we present the biochemical characterization and activity of the extract from the box jellyfish

Indexed as

AnimalsCell Line, TumorComplex MixturesCubozoaHumansNeuritesNeuroprotective AgentsComplex MixturesNeuroprotective Agents

Identifiers

PMID33748281
PMCPMC7954621
OpenAlexW3135636779

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.