ArticleTheranostics2021
FGF19/SOCE/NFATc2 signaling circuit facilitates the self-renewal of liver cancer stem cells.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Gene expression regulation by CaCellular & molecular biology letters · 2026Pooled it
- The role of FGF19-FGFR4 signaling pathway in liver health and disease: Guardian or destroyer.Genes & diseases · 2026Review
- Cancer-associated mitochondrial homeostasis disrupted and retrograde signaling activated.Medical oncology (Northwood, London, England) · 2026Review
- Review
- Nuclear factor of activated T cells as a driver of tumor progression and a target for precision therapy.Animal models and experimental medicine · 2026Review
- SDF4: a novel prognostic biomarker and therapeutic target in hepatocellular carcinoma revealed by integrated multi‑omics analysis.Translational cancer research · 2026Article
- FGF family in health and disease.Molecular biomedicine · 2026Review
- FGF19 in Solid Tumors: Molecular Mechanisms, Metabolic Reprogramming, and Emerging Therapeutic Opportunities.Theranostics · 2026Review
- Early cardioprotective effects of SGLT2i on hypertensive cardiac remodeling via STIM1/Orai1-dependent calcium signaling: beyond blood pressure control.Journal of bioenergetics and biomembranes · 2025Article
- A BPTF-specific PROTAC degrader enhances NK cell-based cancer immunotherapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Article
- Bromocriptine sensitivity in bromocriptine-induced drug-resistant prolactinomas is restored by inhibiting FGF19/FGFR4/PRL.Journal of endocrinological investigation · 2025Article
- Magnesium cantharidate inhibits hepatocellular cancer by targeting RACK1.American journal of translational research · 2025Article
- Regulation of Histone Acetylation During Inflammation Resolution.ImmunoTargets and therapy · 2025Article
- STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma.Genes & diseases · 2024Article
- Fibroblast growth factor receptor 4 deficiency in macrophages aggravates experimental colitis by promoting M1-polarization.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- The Dual Role of the NFATc2/galectin-9 Axis in Modulating Tumor-Initiating Cell Phenotypes and Immune Suppression in Lung Adenocarcinoma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- METTL3 facilitates stemness properties and tumorigenicity of cancer stem cells in hepatocellular carcinoma through the SOCS3/JAK2/STAT3 signaling pathway.Cancer gene therapy · 2024Article
- Article
- Deciphering transcriptome patterns in porcine mesenchymal stem cells promoting phenotypic maintenance and differentiation by key driver genes.Frontiers in cell and developmental biology · 2024Article
- Fibroblast growth factor signaling in macrophage polarization: impact on health and diseases.Frontiers in immunology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 4 institutions in 1 country.
Jingchun WangClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Huakan ZhaoDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
Lu ZhengDepartment of Hepatobiliary Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Yu ZhouDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
Lei WuDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
Yanquan XuClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Xiao ZhangClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Guifang YanDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
Halei ShengClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Rong XinClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Lu JiangClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Juan LeiDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
Jiangang ZhangClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Yu ChenDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
Jin PengClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Qian ChenClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Shuai YangClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Kun YuClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Dingshan LiClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Qichao XieDepartment of Oncology, The Third Affiliated Hospital, Chongqing Medical University, Chongqing 401120, China.
Yongsheng LiClinical Medicine Research Center, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Army Medical University · CNChongqing University · CNXinqiao Hospital · CNChongqing Cancer Hospital · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Calcium SignalingCarcinoma, HepatocellularCell Line, TumorCell Self RenewalFibroblast Growth FactorsHumansLiver NeoplasmsMAP Kinase Signaling SystemNeoplastic Stem CellsNFATC Transcription FactorsPhospholipase C gammaSignal TransductionFGF19 protein, humanFibroblast Growth FactorsNFATC2 protein, humanNFATC Transcription FactorsPhospholipase C gammaFGF19NFATc2, LCSCsself-renewalSOCE
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.