Evidence map›Paper›PMID 33761969›Full record

ArticleEpigenetics & chromatin2021

Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells.

Annika R Seddon, Yusmiati Liau, Paul E Pace, Allison L Miller, Andrew B Das, Martin A Kennedy, Mark B Hampton, Aaron J Stevens

Open access · goldAbstract read
In one paragraph

Article in Epigenetics & chromatin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  4. Article
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  7. Review
  8. Widespread genomicEpigenetics · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Epigenetic Alterations under Oxidative Stress in Stem Cells.Oxidative medicine and cellular longevity · 2022
    Review
  18. Human mScientific reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Annika R SeddonDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand. annika.seddon@otago.ac.nz.ORCID 0000-0001-9702-9077
Yusmiati LiauDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand.
Paul E PaceDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand.
Allison L MillerDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand.
Andrew B DasDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand.
Martin A KennedyDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand.
Mark B HamptonDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand.
Aaron J StevensDepartment of Pathology and Biomedical Science, University of Otago, PO Box 4345, Christchurch, 8140, New Zealand. aaron.stevens@otago.ac.nz.
University of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnvironmental factors, such as oxidative stress, have the potential to modify the epigenetic landscape of cells. We have previously shown that DNA methyltransferase (DNMT) activity can be inhibited by sublethal doses of hydrogen peroxide (H

resultsSublethal H

conclusionsThis research indicates that increased exposure to H

Indexed as

DNA MethylationHydrogen PeroxideGenomeOxidative StressHydrogen PeroxideCancerDNA methylationDNA methyltransferaseEpigeneticsHydrogen peroxideInflammationOxidative stressRedox signalling

Identifiers

PMID33761969
PMCPMC7992848
OpenAlexW3135996847

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.