Evidence map›Paper›PMID 33764739›Full record

ReviewChemical reviews2021

Click Nucleophilic Conjugate Additions to Activated Alkynes: Exploring Thiol-yne, Amino-yne, and Hydroxyl-yne Reactions from (Bio)Organic to Polymer Chemistry.

Joshua C Worch, Connor J Stubbs, Matthew J Price, Andrew P Dove

Abstract readReview
In one paragraph

Review in Chemical reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Journal of the American Chemical Society · 2026
    Article
  9. Thiolated Polymers in 3D Bioprinting: Control of Gelation.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Poly(sarcosine) Lipid Synthesis From COMacromolecular rapid communications · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joshua C WorchSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.ORCID 0000-0002-4354-8303
Connor J StubbsSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.
Matthew J PriceSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.
Andrew P DoveSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.ORCID 0000-0001-8208-9309

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 1,4-conjugate addition reaction between activated alkynes or acetylenic Michael acceptors and nucleophiles (

Indexed as

AlcoholsAlkynesAminesBiopolymersClick ChemistryHydrogelsSulfhydryl CompoundsAlcoholsAlkynesAminesBiopolymersHydrogelsSulfhydryl Compounds

Identifiers

PMID33764739
PMCPMC8227514

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.