Evidence map›Paper›PMID 33765397›Full record

ArticleApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2021

Reduced membrane cholesterol content in skeletal muscle is not essential for greater insulin-stimulated glucose uptake after acute exercise by rats.

Haiyan Wang, Edward B Arias, Gregory D Cartee

Open access · greenAbstract read
In one paragraph

Article in Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Phase angle, muscle tissue, and resistance training.Reviews in endocrine & metabolic disorders · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Haiyan WangMuscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI 48109-1048, USA.
Edward B AriasMuscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI 48109-1048, USA.
Gregory D CarteeMuscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI 48109-1048, USA.
University of Michigan · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Skeletal Muscle Glucose Uptake: Exercise and InsulinR01DK071771 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARTEE, GREGORY D. · 2006 to 2020
$4.5M
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK071771
6 · The paper itself

Abstract

One exercise session can elevate insulin-stimulated glucose uptake (GU) by skeletal muscle, but it is uncertain if this effect is accompanied by altered membrane cholesterol content, which is reportedly inversely related to insulin-stimulated GU. Muscles from sedentary (SED) or exercised 3 h post-exercise (3hPEX) rats were evaluated for GU, membrane cholesterol, and phosphorylation of cholesterol regulatory proteins (pHMCGR

Indexed as

Physical Conditioning, AnimalAnimalsATP Binding Cassette Transporter 1CholesterolGlucoseHydroxymethylglutaryl CoA ReductasesInsulinMuscle, SkeletalPhosphorylationRatsAbca1 protein, ratATP Binding Cassette Transporter 1CholesterolGlucoseHydroxymethylglutaryl CoA ReductasesInsulincaptation de glucosecholestérol membranaireexerciceexerciseglucose uptakemembrane cholesterol

Identifiers

PMID33765397
PMCPMC9359348
OpenAlexW3136434587

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.