Evidence map›Paper›PMID 33778073›Full record

SynthesisBioMed research international2021

Traditional Chinese Medicine Strategy for Patients with Tourette Syndrome Based on Clinical Efficacy and Safety: A Meta-Analysis of 47 Randomized Controlled Trials.

Na Wang, Dong-Dong Qin, Yu-Huan Xie, Xin-Chen Wu, Ding-Yue Wang, Hang-Yang, Xiao-Xuan Li, Lei Xiong, Jing-Hong Liang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Na WangSchool of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.ORCID https://orcid.org/0000-0002-9239-972X
Dong-Dong QinSchool of Basic Medical Science, Yunnan University of Chinese Medicine, Yunnan Kunming 650500, China.
Yu-Huan XieSchool of Basic Medical Science, Yunnan University of Chinese Medicine, Yunnan Kunming 650500, China.
Xin-Chen WuFirst Affiliated Hospital, Yunnan University of Chinese Medicine, Yunnan Kunming 650500, China.
Ding-Yue WangFirst Affiliated Hospital, Yunnan University of Chinese Medicine, Yunnan Kunming 650500, China.
Hang-YangFirst Affiliated Hospital, Yunnan University of Chinese Medicine, Yunnan Kunming 650500, China.
Xiao-Xuan LiFirst Affiliated Hospital, Yunnan University of Chinese Medicine, Yunnan Kunming 650500, China.
Lei XiongSchool of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.ORCID https://orcid.org/0000-0003-3799-7679
Jing-Hong LiangDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.ORCID https://orcid.org/0000-0001-9237-7291

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlthough increasing evidence reveals the efficacy of traditional Chinese medicine (TCM) and its safety on Tourette Syndrome (TS) patients, whether TCM is indeed improving TS remains unclear. The purpose of the current study is to perform a meta-analysis to evaluate the efficacy and safety of TCM on treating TS patients.

methodAn elaborate search strategy was conducted based on several databases including Medline, Embase, Cochrane, Web of Science, CINAHL, CBM, VIP, CNKI, and Wanfang Data in order to identify the relevant randomized controlled trials (RCTs) from their inception to as late as May 1st, 2020. General information and data needing analysis were extracted simultaneously for the necessity of various analyses such as descriptive analysis and metaquantitative analysis.

resultsForty-seven trials with 5437 TS patients in total were eventually included according to our criteria. All trials were conducted in China, and the publication years ranged from 2004 to 2017. In terms of clinical efficacy, clinical symptoms of patients with TCM were more likely to be improved compared with the control group (odds ratio, OR = -1.29, 95% confidence interval, CI: -2.54 to -0.06,

conclusionThe results of our study recommend applying TCM to treat TS patients for better efficacy and safety. Results need to be interpreted cautiously due to certain limitations in our study.

Indexed as

Medicine, Chinese TraditionalChinaHumansRandomized Controlled Trials as TopicTourette Syndrome

Identifiers

PMID33778073
PMCPMC7977981

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.