Evidence map›Paper›PMID 33787378›Full record

ArticleEpilepsy currents2021

Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP.

Gordon F Buchanan, Bruce J Gluckman, Franck K Kalume, Samden Lhatoo, Rama K Maganti, Jeffrey L Noebels, Kristina A Simeone, Mark S Quigg, Milena K Pavlova

Open access · diamondAbstract read
In one paragraph

Article in Epilepsy currents, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 1 country.

Gordon F BuchananDepartment of Neurology and Iowa Neuroscience Institute, 12243University of Iowa Carver College of Medicine, Iowa City, IA, USA.ORCID https://orcid.org/0000-0003-2371-4455
Bruce J GluckmanDepartment of Engineering Science & Mechanics, 8082Penn State University, University Park, PA, USA.ORCID https://orcid.org/0000-0001-7695-2225
Franck K KalumeDepartment of Neurological Surgery, University of Washington and 145793Seattle Children's Research Institute, Seattle, WA, USA.
Samden LhatooDepartment of Neurology, 12339University of Texas McGovern Medical School, Houston, TX, USA.
Rama K MagantiDepartment of Neurology, 5228University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID https://orcid.org/0000-0001-5472-1645
Jeffrey L NoebelsDepartment of Neurology, 3989Baylor College of Medicine, Houston, TX, USA.ORCID https://orcid.org/0000-0002-2887-0839
Kristina A SimeoneDepartment of Pharmacology & Neuroscience, 12282Creighton University School of Medicine, Omaha, NE, USA.
Mark S QuiggDepartment of Neurology, 12350University of Virginia School of Medicine, Charlottesville, VA, USA.
Milena K PavlovaDepartment of Neurology, 1861Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Baylor College of Medicine · USBrigham and Women's Hospital · USCreighton University · USPennsylvania State University · USSeattle Children's Hospital · USThe University of Texas Health Science Center at Houston · USUniversity of Iowa · USUniversity of Virginia · USUniversity of Wisconsin–Madison · US

Funding

Mechanisms of epilepsy-related death in Leigh syndromeR01NS102796 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI KALUME, FRANCK K · 2017 to 2021
$2.1M
NINDS NIH HHS R01 NS102796
6 · The paper itself

Abstract

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises the question of a role for sleep state in regulating of SUDEP. An association with sleep has been identified in a number of studies with patients and in animal models. The focus of this section of the Sleep and Epilepsy Workshop was on identifying and understanding the role for sleep and time of day in the pathophysiology of SUDEP.

Indexed as

comorbiditiesdysregulationepilepsypathophysiological mechanismssleepSUDEP

Identifiers

PMID33787378
PMCPMC8609595
OpenAlexW3145017491

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.