Evidence mapPaperPMID 33787394Full record

ArticleJournal of primary care & community health

Prevalence of the Use of Aspirin and Statins for Preventing Cardiovascular Events in the Colombian Population with Type 2 Diabetes Mellitus: Comparison of 2008 and 2018.

Manuel E Machado-Duque, Diego Arturo Garcia, Melissa Hiromi Emura-Vélez, Andrés Gaviria-Mendoza, Jorge E Machado-Alba

Open access · goldAbstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Manuel E Machado-DuqueUniversidad Tecnológica de Pereira-Audifarma S.A., Pereira, Colombia.
Diego Arturo GarciaFundación Universitaria Autónoma de las Américas, Pereira, Colombia.
Melissa Hiromi Emura-VélezFundación Universitaria Autónoma de las Américas, Pereira, Colombia.
Andrés Gaviria-MendozaUniversidad Tecnológica de Pereira-Audifarma S.A., Pereira, Colombia.
Jorge E Machado-AlbaUniversidad Tecnológica de Pereira-Audifarma S.A., Pereira, Colombia.ORCID 0000-0002-8455-0936
Technological University of Pereira · COFundación Universitaria Autónoma De Las Américas · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 diabetes mellitus (T2DM) greatly increases cardiovascular risk. Primary and secondary cardiovascular prevention lead to lower cardiovascular events, improved quality of life and lower costs related to complications.

objectiveTo estimate the proportion of patients with T2DM undergoing drug therapy for cardiovascular prevention (aspirin and statins) in Colombia and to describe the change in patterns of use between 2008 and 2018.

methodsThis was a cross-sectional study comparing prescriptions for aspirin and statins in 2008 and in 2018 in outpatients diagnosed with T2DM. Records were obtained from a national drug claim database. The proportion of use of cardiovascular prevention drugs and antidiabetic drugs, medications for comorbidities and sociodemographic variables were analyzed for both periods.

resultsIn total, 26 742 patients in 2008 and 188 321 in 2018 with a diagnosis of T2DM treated with antidiabetic drugs were identified, among whom 57.5% and 44.2% received aspirin and 44.9% and 60.2% received statins, respectively. The use of high-intensity statins increased from 1.1% in 2008 to 95.2% in 2018. The probabilities of receiving drugs in 2008 and in 2018 were higher for men (OR: 1.12, 95% CI: 1.06-1.17 and OR: 1.26, 95% CI: 1.23-1.28, respectively), for those persons over 75 years of age (OR: 6.5, 95% CI: 5.3-7.9 and OR: 5.8, 95% CI: 5.4-6.2) and for those who also received clopidogrel (OR: 5.8, 95% CI: 4.4-7.6 and OR: 2.2, 95% CI: 2.1-2.4).

conclusionsThe use of high-intensity statins in patients with T2DM has increased significantly in the last decade, which should reduce cardiovascular events, morbidity and mortality.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Hydroxymethylglutaryl-CoA Reductase InhibitorsPharmaceutical PreparationsAspirinColombiaCross-Sectional StudiesHumansMalePrevalenceQuality of LifeAspirinHydroxymethylglutaryl-CoA Reductase InhibitorsPharmaceutical Preparationsaspirincardiovascular diseaseshydroxymethylglutaryl-CoA reductase inhibitorshypolipidemic agentspharmacoepidemiologyType 2 diabetes mellitus

Identifiers

PMID33787394
PMCPMC8772352
OpenAlexW3141476417

What Socratic holds

Texttitle and abstract
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.