ReviewIntegrative and comparative biology2021
Light at Night and Disrupted Circadian Rhythms Alter Physiology and Behavior.
Review in Integrative and comparative biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Artificial Light at Night Consistently Impacts Avian Physiology and Behaviour: A Meta-Analysis.Ecology letters · 2026Pooled it
- Nocturnal Dim Blue Light Is Associated with Splenic Immune Dysregulation and Altered CORT-GR Signalling in High-Fat-Diet-Fed Mice.Antioxidants (Basel, Switzerland) · 2026Article
- The Circadian-Light-Hygiene Hypothesis: A Potential Modulator of Fertility and Birthrate Trends.Biology · 2026Review
- Research progress and future directions in circadian rhythms for uterine‑related diseases (Review).Molecular medicine reports · 2026Review
- The ecological importance of natural dark nights for circadian organization, metabolism and reproduction in birds.BMC ecology and evolution · 2026Review
- Association between systemic immune-inflammatory index and circadian syndrome: Data from NHANES 2005 to 2018.Medicine · 2026Article
- Wild-Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Swimming behavior of Daphnia dentifera is influenced by Australozyma monospora infection.PloS one · 2026Article
- Short-term continuous light exposure induces hippocampal rhythmic and functional alterations: a multi-timepoint metabolomics study.Frontiers in molecular biosciences · 2026Article
- The Effects of Light on Vertebrate Welfare: A Review.Animals : an open access journal from MDPI · 2025Review
- Article
- Effects of air and light pollution on brain and behavioral function: Potential synergy.Neuroscience and biobehavioral reviews · 2025Review
- Naturalight: A controlled illuminated environment to study light exposure impact on behavior and cognition in freely moving rats.HardwareX · 2025Article
- Light at night negatively affects mood in diurnal primate-like tree shrews via a visual pathway related to the perihabenular nucleus.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Light Affects Host-Symbiont Dynamics in the Non-Photosynthetic Social Amoeba Symbiosis.Ecology and evolution · 2025Article
- The Circadian Rhythm of Asthma Immune Metabolism.Journal of immunology research · 2025Review
- Circadian influences on central nervous system barriers and the glymphatic system.Frontiers in physiology · 2025Review
- The association between using screen in the dark and depressive symptoms: a longitudinal study among Chinese adolescents.Frontiers in psychiatry · 2025Article
- RPS27A as a potential clock-related diagnostic biomarker for myocardial infarction: Comprehensive bioinformatics analysis and experimental validation.Clinics (Sao Paulo, Brazil) · 2025Article
- Dim light at night unmasks sex-specific differences in circadian and autonomic regulation of cardiovascular physiology.Communications biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Life on earth has evolved during the past several billion years under relatively bright days and dark nights. Virtually all organisms on the planet display an internal representation of the solar days in the form of circadian rhythms driven by biological clocks. Nearly every aspect of physiology and behavior is mediated by these internal clocks. The widespread adoption of electric lights during the past century has exposed animals, including humans, to significant light at night (LAN) for the first time in our evolutionary history. Importantly, endogenous circadian clocks depend on light for synchronization with the external daily environment. Thus, LAN can derange temporal adaptations. Indeed, disruption of natural light-dark cycles results in several physiological and behavioral changes. In this review, we highlight recent evidence demonstrating how LAN exposure can have serious implications for adaptive physiology and behavior, including immune, endocrine, and metabolic function, as well as reproductive, foraging, and migratory behavior. Lastly, strategies to mitigate the consequences of LAN on behavior and physiology will be considered.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.