ArticleReproductive sciences (Thousand Oaks, Calif.)2022
Adolescent Transgender Females Present Impaired Semen Quality That Is Suitable for Intracytoplasmic Sperm Injection Even Before Initiating Gender-Affirming Hormone Treatment.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- The impact of tucking on fertility among transgender women: A systematic review.International journal of transgender health · 2026Review
- Gender-affirming hormone therapy: Effect on semen quality and use of fertility preservation.Andrology · 2026Review
- Semen Cryopreservation and Semen Quality in Transfeminine Adolescents Prior to Hormone Therapy.Journal of the Endocrine Society · 2025Article
- The experience of transfeminine adolescents and their parents regarding fertility preservation via testicular sperm extraction (TESE): a qualitative study.Human reproduction (Oxford, England) · 2024Article
- Clinical management of transgender and non-binary patients in the fertility preservation service: Current evidence.International journal of transgender health · 2024Review
- Fertility, Contraception, and Fertility Preservation in Trans Individuals.Deutsches Arzteblatt international · 2023Review
- The return of spermatogenesis in transgender women ceasing gender-affirming hormone therapy.Cell reports. Medicine · 2023Article
- Fertility preservation options for transgender and nonbinary individuals.Therapeutic advances in endocrinology and metabolism · 2023Review
- Fertility preservation in pediatric healthcare: a review.Frontiers in endocrinology · 2023Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to determine the semen quality and cryopreservation outcomes among adolescent transgender females at the time of fertility preservation (FP) before initiating gender-affirming hormone (GAH) treatment. This retrospective cohort study included 26 adolescent transgender females who underwent FP in our Fertility Institute between 06/2013 and 10/2020. Pre-freezing semen parameters were compared to WHO 2010 reference values. Post-thaw semen parameters were used to determine the adequate assisted reproductive technology (ART). A multivariate linear regression analysis was performed to assess the impact of medical and lifestyle factors on semen quality. The mean age at which adolescent transgender females underwent FP was 16.2 ± 1.38 years. The median values of all semen parameters in our study group were significantly lower compared to the WHO data, including volume (1.46 mL vs 3.2 mL, respectively, P = 0.001 ), sperm concentration (28 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.