SynthesisJournal of occupational health2021
Protective effects of vitamins/antioxidants on occupational noise-induced hearing loss: A systematic review.
Synthesis in Journal of occupational health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Protective effects of vitamins/antioxidants on occupational noise-induced hearing loss: A systematic review.Journal of occupational health · 2021Pooled it
- Luteolin Protects Against Noise-Induced Hearing Loss via Mitigating Oxidative Stress and Apoptosis, With Potential Regulation of the EGR1/SPRY4 Axis.CNS neuroscience & therapeutics · 2026Article
- A review of occupational noise-induced hearing loss: focus on mechanisms and preventive measures.British medical bulletin · 2025Review
- Exploring AAV-Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Electrophysiological Effects of Intratympanic Retinoic Acid Application Following Acoustic Trauma in Rats.The journal of international advanced otology · 2025Article
- Noise-induced hearing loss and blood factors: results from a comprehensive cross-sectional study in Iran.BMC public health · 2025Article
- Article
- Developing and validating a risk assessment method for noise-induced hearing loss in workers.Heliyon · 2024Article
- The impact of noise-induced hearing loss on individual job performance: exploring the role of aggression and work-related quality of life.BMC psychology · 2024Article
- Pathogenesis and New Pharmacological Approaches to Noise-Induced Hearing Loss: A Systematic Review.Antioxidants (Basel, Switzerland) · 2024Review
- Variations in the Cadherin 23 Gene Associated With Noise-Induced Hearing Loss.Journal of multidisciplinary healthcare · 2024Article
- Association between oxidative balance score and hearing loss: a cross-sectional study from the NHANES database.Frontiers in nutrition · 2024Article
- Article
- Redox homeostasis dysregulation in noise-induced hearing loss: oxidative stress and antioxidant treatment.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023Review
- Antioxidant Therapy as an Effective Strategy against Noise-Induced Hearing Loss: From Experimental Models to Clinic.Life (Basel, Switzerland) · 2023Review
- Noise-Induced Hearing Loss.Journal of clinical medicine · 2023Review
- A Bayesian network model to predict the role of hospital noise, annoyance, and sensitivity in quality of patient care.BMC nursing · 2022Article
- Development andFrontiers in neurology · 2022Article
- Association of dietary factors with noise-induced hearing loss in Korean population: A 3-year national cohort study.PloS one · 2022Article
- From sound waves to molecular and cellular mechanisms: Understanding noise‑induced hearing loss and pioneering preventive approaches (Review).Medicine internationalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesOccupational noise-induced hearing loss (NIHL) due to industrial, military, and other job -related noise exposure can cause harmful health issues to occupied workers, but may also be potentially preventable. Vitamins/antioxidant have been studied as therapeutic strategies to prevent and/or delay the risks of human diseases as well as NIHL .So, this study was conducted to systematically review the protective effects of vitamins/antioxidants on occupational NIHL.
methodsOnline databases including PubMed/Medline, Scopus, Web of Science, EMBASE, Science Direct, and Google Scholar were systematically searched up to 12 January 2021. Based on 6336 potentially relevant records identified through the initial search in the databases, 12 full-text publications were retrieved, one of which can be viewed as two separate trials, because it has studied the effects of two different antioxidants (ginseng and NAC) on NIHL, separately.
resultsA review of the studies shows that vitamin B12, folic acid, and N-acetylcysteine (NAC) have a considerable protective effect on NIHL. However, these protective effects are not yet specified in different frequencies. The findings regarding the protective effects of other antioxidants are inconsistent in this field.
conclusionVitamin B12, folic acid, and NAC may have a protective effect as an antioxidant on reducing occupational hearing loss. For a conclusive evidence of vitamin/antioxidant protective therapies, future studies with precise criteria for noise exposure and similar outcome parameters are required.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.