ArticleORL; journal for oto-rhino-laryngology and its related specialties2021
Sustained Chemosensory Dysfunction during the COVID-19 Pandemic.
Article in ORL; journal for oto-rhino-laryngology and its related specialties, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 30 citations in OpenAlex.
- Impact of Long COVID-19 on Health Outcomes Among Adults With Preexisting Cardiovascular Disease and Hypertension: A Systematic Review.CJC open · 2024Review
- Evaluation of children and adults with post-COVID-19 persistent smell, taste and trigeminal chemosensory disorders: A hospital based study.World journal of clinical pediatrics · 2023Article
- Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection.Journal of clinical medicine · 2023Article
- What Is Different in COVID-19-Associated Olfactory Loss from Classical Postinfectious Olfactory Impairment?ORL; journal for oto-rhino-laryngology and its related specialties · 2023Article
- Reply: taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis.Chemical senses · 2023Article
- Analysis of Prevalence and Predictive Factors of Long-Lasting Olfactory and Gustatory Dysfunction in COVID-19 Patients.Life (Basel, Switzerland) · 2022Article
- The Effects of Olfactory Loss and Parosmia on Food and Cooking Habits, Sensory Awareness, and Quality of Life-A Possible Avenue for Regaining Enjoyment of Food.Foods (Basel, Switzerland) · 2022Article
- Incidence and duration of self-reported hearing loss and tinnitus in a cohort of COVID-19 patients with sudden chemosensory loss: A STROBE observational study.European annals of otorhinolaryngology, head and neck diseases · 2022Observational
- Your Money or Your Sense of Smell? A Comparative Analysis of the Sensory and Psychological Value of Olfaction.Brain sciences · 2022Article
- Relationship between Recovery from COVID-19-Induced Smell Loss and General and Oral Health Factors.Medicina (Kaunas, Lithuania) · 2022Article
- Self-reported olfactory and gustatory dysfunctions in COVID-19 patients: a 1-year follow-up study in Foggia district, Italy.BMC infectious diseases · 2022Article
- Taste loss as a distinct symptom of COVID-19: A systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2021Article
- Taste Dysfunction and Long COVID-19.Frontiers in cellular and infection microbiology · 2021Article
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChemosensory dysfunction (CD) has proven valuable in prediction of COVID-19, as it is a frequent and specific symptom of the disease. The aim of this study was to investigate the duration of CD in patients with sudden subjective olfactory and/or gustatory loss during the SARS-CoV-2 pandemic. The secondary aim was to identify possible prognostic factors for the duration of CD.
methodsAn online baseline questionnaire was designed to assess subjective CD. Three rounds of follow-up questionnaires were sent out to any participants with persistent CD in 6-week intervals, prospectively assessing subjective chemosensory function and extending the follow-up time of this cohort significantly.
resultsIn total, 467 participants completed the baseline questionnaire. The most significant improvement and recovery of chemosensory function was observed within the first month after the initial loss. Rates became stagnant after about 2 months, and only little improvement and recovery was seen after 2-4 months. After a mean follow-up of 95.9 days (olfactory dysfunction) and 94.0 days (gustatory dysfunction), 86.7% of participants reported gustatory improvement and 82.6% reported olfactory improvement, while 55.0% reported full gustatory recovery and 43.8% reported full olfactory recovery. Female gender was associated with better improvement of gustatory function. High subjective severity of chemosensory loss was associated with lower rates of olfactory and gustatory recovery as well as improvement of olfactory function. Young age was not associated with a better prognosis. DISCUSSION/
conclusionRates of improvement and recovery of chemosensory function decreased after 2-4 months after initial chemosensory loss, possibly indicating that prolonged and perhaps permanent chemosensory loss may be a complication of SARS-CoV-2 infections. High subjective severity of CD may worsen the prognosis for improvement and recovery of chemosensory function.
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