Evidence map›Paper›PMID 33790313›Full record

ArticleScientific reports2021

Garcinia mangostana extract and curcumin ameliorate oxidative stress, dyslipidemia, and hyperglycemia in high fat diet-induced obese Wistar albino rats.

Ranyah Shaker M Labban, Hanan A Alfawaz, Ahmed T Almnaizel, May N Al-Muammar, Ramesa Shafi Bhat, Afaf El-Ansary

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Hypoglycemic activity ofFrontiers in pharmacology · 2024
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Mangostanin, a Xanthone Derived fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ranyah Shaker M LabbanDepartment of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Hanan A AlfawazDepartment of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Ahmed T AlmnaizelPrince Naif for Health Research Center, King Saud University, Riyadh, Saudi Arabia.
May N Al-MuammarDepartment of Community Health, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Ramesa Shafi BhatBiochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Afaf El-AnsaryCentral Laboratory, Female Centre for Scientific and Medical Studies, King Saud University, Riyadh, Saudi Arabia. afafkelansary@gmail.com.
King Saud University · SAMinistry of Health · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to explore the effects of Garcinia mangostana (mangosteen) and Curcuma longa independently and synergistically in modulating oxidative stress, dyslipidemia, and hyperglycemia commonly observed in high-fat diet-induced obesity in rodent models. Male albino Wistar rats were divided into eight experimental groups, fed on a normal diet or high-fat diet (HFD), then given mangosteen extract (400 mg /kg /day) and/or curcumin (80 mg/kg /day) for 6 weeks. Oxidative stress markers, glucose, and lipid fractions were measured in the sera. Mangosteen pericarp extract (MPE) induced a remarkable decrease in BMI (from 0.86 to 0.81 gm/cm

Indexed as

AnimalsAntioxidantsCurcuminDiet, High-FatDyslipidemiasGarcinia mangostanaHyperglycemiaHypoglycemic AgentsMaleObesityPlant ExtractsRatsRats, WistarAntioxidantsCurcuminHypoglycemic AgentsPlant Extracts

Identifiers

PMID33790313
PMCPMC8012579
OpenAlexW3147089953

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.