Evidence map›Paper›PMID 33792900›Full record

ArticleComprehensive Physiology2021

The Calcium Signaling Mechanisms in Arterial Smooth Muscle and Endothelial Cells.

Matteo Ottolini, Swapnil K Sonkusare

Open access · greenAbstract read
In one paragraph

Article in Comprehensive Physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  4. Article
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  8. Article
  9. Article
  10. Review
  11. An In Vivo Model of Estrogen Supplementation Concerning the Expression of CaJournal of cardiovascular development and disease · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Cracking the Endothelial Calcium (CaInternational journal of molecular sciences · 2023
    Review
  16. Review
  17. Review
  18. Review
  19. Novel Smooth Muscle CaCirculation · 2022
    Article
  20. The Potential Role of Everlasting Flower (Antioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matteo OttoliniDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia, USA.
Swapnil K SonkusareDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia, USA.
University of Virginia · US

Funding

Paracrine TNF signaling impairs endothelial TRPV4 microdomains in obesityR01HL142808 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2019 to 2026
$4.4M
Flow-Activated Calcium Signaling Microdomains in Small Pulmonary ArteriesR01HL146914 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2019 to 2026
$3.8M
A novel TRPV4-eNOS signaling pathway in pulmonary endotheliumR56HL138496 · NHLBI · UNIVERSITY OF VIRGINIA · PI SONKUSARE, SWAPNIL K. · 2017 to 2017
$403k
NHLBI NIH HHS R01 HL142808NHLBI NIH HHS R01 HL146914NHLBI NIH HHS R56 HL138496
6 · The paper itself

Abstract

The contractile state of resistance arteries and arterioles is a crucial determinant of blood pressure and blood flow. Physiological regulation of arterial contractility requires constant communication between endothelial and smooth muscle cells. Various Ca

Indexed as

Calcium SignalingEndothelial CellsArteriesArteriolesCalciumMuscle, Smooth, VascularCalcium

Identifiers

PMID33792900
PMCPMC10388069
OpenAlexW3143706930

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.