ReviewCirculation research2021
Hypertension in Low- and Middle-Income Countries.
Review in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 268 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
268 citing papers in PubMed, 6 syntheses or guidelines pooled it, 391 citations in OpenAlex.
- A Systematic Review of the Role of Recreational Activities and Dietary Management in Treating Hypertension and Hyperglycaemia in Adults in Low- and Middle-Income Countries.International journal of environmental research and public health · 2026Pooled it
- Assessing implementation outcomes from studies addressing medication adherence for hypertension management in Sub-Saharan Africa: a systematic review.BMC public health · 2025Pooled it
- Efficacy and Safety of Low-Dose Triple Single Pill Combination Versus Standard Care in the Management of Hypertension in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis of Three Randomized Controlled Trials.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Pooled it
- Self-management interventions for common long-term conditions in low- and middle-income countries: a synthesis of current evidence.Journal of global health · 2025Pooled it
- The impact of hypertension prevention and modification on dementia burden: A systematic review of economic studies.The journal of prevention of Alzheimer's disease · 2025Pooled it
- Consideration of inequalities in effectiveness trials of mHealth applications - a systematic assessment of studies from an umbrella review.International journal for equity in health · 2024Pooled it
- Feasibility study of a novel mHealth clinical decision support application to enable community health workers to manage hypertension in rural Guatemala.Journal of global health · 2026Trial
- Partnerships and organizational capacity drive sustainability of integrated hypertension-HIV care in primary health care in Uganda.BMC health services research · 2026Trial
- A prospective cohort study of the SEARCH integrated HIV/hypertension community health worker-led intervention in rural Kenya and Uganda.Journal of the International AIDS Society · 2025Trial
- Learning implementation of a guideline based decision support system to improve hypertension treatment in primary care in China: pragmatic cluster randomised controlled trial.BMJ (Clinical research ed.) · 2024Trial
- The effect of internal migration on blood pressure among a cohort of young adults in South Africa.Social science & medicine (1982) · 2026Article
- Individual income and blood pressure control after antihypertensive treatment initiation accounting for regional variation: a Japanese nationwide study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Mapping Pharmacogenomic Determinants of Adverse Drug Reactions in Hypertension: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Sex Differences in Sleep Duration and Quality: Implications for Hypertension Risk.Current hypertension reports · 2026Review
- Gastrointestinal digestion enhances the release of bioactive peptides from yogurt.European journal of nutrition · 2026Article
- Comparative Analysis of Hypertension Stages Prevalence and Associated Factors in Bangladesh: Evidence From BDHS 2017-18 and 2022.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Echo Chambers: Bias and Representation in Cardiac Imaging Datasets for Artificial Intelligence.Current cardiology reports · 2026Review
- Global DNA methylation and hypertension control Vis-À-Vis lipids: an exploratory population based study from rural Punjab, India.Journal of human hypertension · 2026Article
- Assessing quality gaps in hypertensive disorders of pregnancy care in China: an unannounced standardised patient study protocol.BMJ open · 2026Article
- Global Burden of Intracerebral Hemorrhage, 1990-2021, and Projections to 2050: A Global Burden of Disease Study 2021.Journal of Korean medical science · 2026Article
208 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 4 countries.
Funding
Abstract
In recent decades low- and middle-income countries (LMICs) have been witnessing a significant shift toward raised blood pressure; yet in LMICs, only 1 in 3 are aware of their hypertension status, and ≈8% have their blood pressure controlled. This rising burden widens the inequality gap, contributes to massive economic hardships of patients and carers, and increases costs to the health system, facing challenges such as low physician-to-patient ratios and lack of access to medicines. Established risk factors include unhealthy diet (high salt and low fruit and vegetable intake), physical inactivity, tobacco and alcohol use, and obesity. Emerging risk factors include pollution (air, water, noise, and light), urbanization, and a loss of green space. Risk factors that require further in-depth research are low birth weight and social and commercial determinants of health. Global actions include the HEARTS technical package and the push for universal health care. Promising research efforts highlight that successful interventions are feasible in LMICs. These include creation of health-promoting environments by introducing salt-reduction policies and sugar and alcohol tax; implementing cost-effective screening and simplified treatment protocols to mitigate treatment inertia; pooled procurement of low-cost single-pill combination therapy to improve adherence; increasing access to telehealth and mHealth (mobile health); and training health care staff, including community health workers, to strengthen team-based care. As the blood pressure trajectory continues creeping upward in LMICs, contextual research on effective, safe, and cost-effective interventions is urgent. New emergent risk factors require novel solutions. Lowering blood pressure in LMICs requires urgent global political and scientific priority and action.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.