ArticleOptics letters2021
Imaging localized fast optical signals of neural activation with optical coherence tomography in awake mice.
Article in Optics letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- A neurorecording toolkit for longitudinal assessments of transplanted human cortical organoidsbioRxiv : the preprint server for biology · 2025Article
- Optical coherence tomography enables longitudinal evaluation of cell graft-directed remodeling in stroke lesions.Experimental neurology · 2025Article
- Non-destructive viability assessment of cancer cell spheroids using dynamic optical coherence tomography with trypan blue validation.Biomedical optics express · 2024Article
- High spatiotemporal mapping of cortical blood flow velocity with an enhanced accuracy.Biomedical optics express · 2024Article
- Time-Lagged Functional Ultrasound for Multi-Parametric Cerebral Hemodynamic Imaging.IEEE transactions on medical imaging · 2024Article
- Measurements of slow tissue dynamics with short-separation speckle contrast optical spectroscopy.Biomedical optics express · 2023Article
- All-optical observation on activity-dependent nanoscale dynamics of myelinated axons.Neurophotonics · 2023Article
- Fast and slow light-induced changes in murine outer retina optical coherence tomography: complementary high spatial resolution functional biomarkers.PNAS nexus · 2022Article
- Neurophotonic tools for microscopic measurements and manipulation: status report.Neurophotonics · 2022Article
- Measuring neuronal activity with diffuse correlation spectroscopy: a theoretical investigation.Neurophotonics · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We report optical coherence tomography (OCT) imaging of localized fast optical signals (FOSs) arising from whisker stimulation in awake mice. The activated voxels were identified by fitting the OCT intensity signal time course with a response function over a time scale of a few hundred milliseconds after the whisker stimulation. The significantly activated voxels were shown to be localized to the expected brain region for whisker stimulation. The ability to detect functional stimulus-evoked, depth-resolved FOS with intrinsic contrast from the cortex provides a new tool for neural activity studies.
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Registered trials
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