Evidence map›Paper›PMID 33794320›Full record

SynthesisProgress in neuro-psychopharmacology & biological psychiatry2021

Impulsivity and compulsivity in binge eating disorder: A systematic review of behavioral studies.

Meagan M Carr, Ashley A Wiedemann, Grace Macdonald-Gagnon, Marc N Potenza

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Progress in neuro-psychopharmacology & biological psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
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  14. Observational
  15. Review
  16. Behaviourally assessed negative urgency is uniquely associated with binge-eating frequency.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  17. Article
  18. Habitual behavioural control moderates the relation between daily perceived stress and purging.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Meagan M CarrDepartment of Psychiatry, Yale School of Medicine, 300 George St., New Haven, CT 06511, United States of America.
Ashley A WiedemannDepartment of Psychiatry, Yale School of Medicine, 300 George St., New Haven, CT 06511, United States of America.
Grace Macdonald-GagnonDepartment of Psychiatry, Yale School of Medicine, 300 George St., New Haven, CT 06511, United States of America.
Marc N PotenzaDepartment of Psychiatry, Yale School of Medicine, 300 George St., New Haven, CT 06511, United States of America; Connecticut Mental Health Center, 34 Park St., New Haven, CT 06511, United States of America; Connecticut Council on Problem Gambling, 100 Great Meadow Rd, Wethersfield, CT 06109, United States of America; Child Study Center, Yale School of Medicine, 230 S Frontage Rd., New Haven, CT 06519, United States of America; Department of Neuroscience, Yale University, One Church Street, New Haven, CT 06510, United States of America. Electronic address: marc.potenza@yale.edu.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research Training Program in Substance Use PreventionT32DA019426 · NIDA · YALE UNIVERSITY · PI TAMI P SULLIVAN · 2005 to 2026
$7.5M
Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Cognitive-Behavioral and Pharmacologic Treatment of Binge Eating DisorderR01DK114075 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2018 to 2022
$3.6M
Neurocognitive fMRI Mechanisms of CBT and Lisdexamfetamine Outcomes in Obesity and BEDR01DK121551 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M, POTENZA, MARC N · 2019 to 2023
$1.8M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS T32 DA007238NIDA NIH HHS T32 DA019426NIDDK NIH HHS R01 DK114075NIDDK NIH HHS R01 DK121551
6 · The paper itself

Abstract

backgroundBinge eating disorder (BED) often includes impulsive and compulsive behaviors related to eating behavior and food. Impulsivity and compulsivity generally may contribute to the etiology and maintenance of multiple psychiatric disorders including BED. This review aimed to identify and synthesize available behavioral studies of impulsivity and compulsivity among individuals with BED.

methodA systematic search was performed focusing on BED and specific facets of impulsivity (rapid response and choice) and compulsivity (set-shifting, cognitive flexibility, and/or habit learning). All case-control studies comparing adults with either full-threshold or subthreshold BED to individuals with normal weight, overweight/obesity, or other eating disorders (e.g., bulimia nervosa) were included.

resultsThirty-two studies representing 29 unique samples met inclusion criteria. Increased choice impulsivity was observed among individuals with BED relative to individuals with normal weight. There were mixed findings and/or a lack of available evidence regarding rapid response impulsivity and compulsivity. The presence of between-group differences was not dependent on sample characteristics (e.g., full or sub threshold BED diagnosis, or treatment-seeking status). Heterogeneity relating to covariates, task methodologies, and power limited conclusions.

conclusionsLiterature supports a postive association between choice impulsivity and BED. More research is needed to determine if individuals with BED demonstrate elevated levels of either rapid response impulsivity or types of compulsivity. Careful selection of covariates and consideration of task methodologies and power would aid future research.

Indexed as

Binge-Eating DisorderCase-Control StudiesCompulsive BehaviorFeeding BehaviorHumansImpulsive BehaviorNeuropsychological TestsObesityBinge-eating disorderCognitionCompulsivityDelay discountingImpulsivityObesity

Identifiers

PMID33794320
PMCPMC8222068
OpenAlexW3147519121

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.